Results 21 to 30 of about 15,461 (258)
IEEE Access, 2018 This paper presents the analysis of the three parallel triplicated redundancy models: model with one active and two standby components, model with one standby and two active components, and model with three active components.
Yutae Lee
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Virtual series-system models of imperfect repair [PDF]
Reliability Engineering & System Safety, 2019 Novel models of imperfect repair are fitted to classic reliability datasets. The models suppose that a virtual system comprises a component and a remainder in series. On failure of the component, the component is renewed, and on failure of the remainder, the component is renewed\ud and the remainder is minimally repaired.
Ibrahim Nafisah +3 more
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Maintenance Modeling for a Multi-State System Under Competing Failures and Imperfect Repairs
MathematicsA condition-based maintenance modeling approach is proposed for a multi-state system under competing failures and imperfect repairs. The system experiences three states (normal, defective and failed) over its lifecycle. Two competing failure processes, i.
Yanjing Zhang, Xiaohua Meng
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Imperfect Maintenance Policy for a Two-Machine One-Buffer System Based on Markov Decision Process
Shanghai Jiaotong Daxue xuebao, 2021 To solve the problem of machine maintenance optimization of degraded systems, the preventive maintenance policy of a two-machine one-buffer production system is studied. First, random degradations of both machines are considered.
TIAN Xueyan, WANG Mengya, PAN Ershun
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Nonparametric Methods for Imperfect Repair Models
The Annals of Statistics, 1992 An appropriate probability model for the age-dependent minimal repair model of \textit{H. W. Block}, \textit{W. S. Borges} and \textit{T. H. Savits} [J. Appl. Probab. 22, 370-385 (1985; Zbl 0564.60084)] is developed and a counting process approach is used to extend the large sample theorems of \textit{L. R. Whitaker} and \textit{F. J. Samaniego} [J. Am.
Hollander, Myles +2 more
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Yeast pol4 promotes tel1-regulated chromosomal translocations. [PDF]
PLoS Genetics, 2013 DNA double-strand breaks (DSBs) are one of the most dangerous DNA lesions, since their erroneous repair by nonhomologous end-joining (NHEJ) can generate harmful chromosomal rearrangements.
Jose F Ruiz +4 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Is non-homologous end-joining really an inherently error-prone process? [PDF]
PLoS Genetics, 2014 DNA double-strand breaks (DSBs) are harmful lesions leading to genomic instability or diversity. Non-homologous end-joining (NHEJ) is a prominent DSB repair pathway, which has long been considered to be error-prone.
Mireille Bétermier +2 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Unobserved heterogeneity in stable imperfect repair models
Reliability Engineering & System Safety, 2020 Abstract This study investigates the effect of heterogeneity on the failures of repairable systems that undergo imperfect repairs, which are extensively used in reliability engineering. When considering a group of similar systems, the assumption that the repair processes are independent and identically distributed becomes questionable owing to the ...
Xingheng Liu +3 more
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