Results 31 to 40 of about 733,404 (291)

Maintenance Modeling for a Multi-State System Under Competing Failures and Imperfect Repairs

open access: yesMathematics
A condition-based maintenance modeling approach is proposed for a multi-state system under competing failures and imperfect repairs. The system experiences three states (normal, defective and failed) over its lifecycle. Two competing failure processes, i.
Yanjing Zhang, Xiaohua Meng
doaj   +1 more source

Imperfect Maintenance Policy for a Two-Machine One-Buffer System Based on Markov Decision Process

open access: yesShanghai Jiaotong Daxue xuebao, 2021
To solve the problem of machine maintenance optimization of degraded systems, the preventive maintenance policy of a two-machine one-buffer production system is studied. First, random degradations of both machines are considered.
TIAN Xueyan, WANG Mengya, PAN Ershun
doaj   +1 more source

Nonparametric Methods for Imperfect Repair Models

open access: yesThe Annals of Statistics, 1992
An appropriate probability model for the age-dependent minimal repair model of \textit{H. W. Block}, \textit{W. S. Borges} and \textit{T. H. Savits} [J. Appl. Probab. 22, 370-385 (1985; Zbl 0564.60084)] is developed and a counting process approach is used to extend the large sample theorems of \textit{L. R. Whitaker} and \textit{F. J. Samaniego} [J. Am.
Hollander, Myles   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Unobserved heterogeneity in stable imperfect repair models

open access: yesReliability Engineering & System Safety, 2020
Abstract This study investigates the effect of heterogeneity on the failures of repairable systems that undergo imperfect repairs, which are extensively used in reliability engineering. When considering a group of similar systems, the assumption that the repair processes are independent and identically distributed becomes questionable owing to the ...
Xingheng Liu   +3 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Yeast pol4 promotes tel1-regulated chromosomal translocations. [PDF]

open access: yesPLoS Genetics, 2013
DNA double-strand breaks (DSBs) are one of the most dangerous DNA lesions, since their erroneous repair by nonhomologous end-joining (NHEJ) can generate harmful chromosomal rearrangements.
Jose F Ruiz   +4 more
doaj   +1 more source

Repairing and meshing imperfect shapes with Delaunay refinement [PDF]

open access: yes2009 SIAM/ACM Joint Conference on Geometric and Physical Modeling, 2009
As a direct consequence of software quirks, designer errors, and representation flaws, often three-dimensional shapes are stored in formats that introduce inconsistencies such as small gaps and overlaps between surface patches. We present a new algorithm that simultaneously repairs imperfect geometry and topology while generating Delaunay meshes of ...
Oleksiy Busaryev   +2 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Imperfect Repair Strategies for Two-Dimensional Warranty

open access: yes, 2010
When a repairable product under warranty fails, the manufacturer (warrantor) has the choice to either repair or replace the failed product. When repairing a failed product, the degree of repair which affects the working condition of the product can vary,
Varnosafaderani, Sima Rouhollahi (11698897)   +2 more
core   +1 more source

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