Results 51 to 60 of about 100,307 (296)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Ambiguous Bodies, Biopower and the Ideologies of Science Fiction [PDF]
, 2016 Contemporary Hollywood film narrates the fear of monstrous science; attending to the modulations of medicine, capital and the body. The filmic body is employed to illustrate the power of the new biotechnologies to create and sustain life and the new ...
Flynn, Susan
core
Scheduling of Multicast and Unicast Services under Limited Feedback by using Rateless Codes
, 2014 Many opportunistic scheduling techniques are impractical because they require accurate channel state information (CSI) at the transmitter. In this paper, we investigate the scheduling of unicast and multicast services in a downlink network with a very ...
Kim, Kyu-Han +3 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Estimation of component redundancy in optimal age maintenance [PDF]
, 2012 The classical Optimal Age-Replacement defines the maintenance strategy based on the equipment failure consequences. For severe consequences an early equipment replacement is recommended. For minor consequences the repair after failure is proposed.
Garção, José +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Optimal number of imperfect repairs for deteriorating systems [PDF]
International Journal of Industrial Engineering and Production ResearchA periodic maintenance policy through either an imperfect repair or replacement is proposed for a repairable system. It is assumed that the system is subject to an inverse Gaussian degradation process.
Khatereh Rajinia, Mostafa Razmkhah
doaj
Supporting group maintenance through prognostics-enhanced dynamic dependability prediction [PDF]
, 2017 Condition-based maintenance strategies adapt maintenance planning through the integration of online condition monitoring of assets. The accuracy and cost-effectiveness of these strategies can be improved by integrating prognostics predictions and ...
Aizpurua, J. I. +9 more
core +1 more source
, 2012 Repair is a type of maintenance carried out on an item after it fails. A failure may occur any time, hence the times to repair cannot be pre-specified. Methods used to model times to failures are normally stochastic processes such as the renewal process and the homogeneous Poisson process, depending on the effectiveness of a repair.
Luo, M., Wu, S., Scarf, P.
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source