Results 61 to 70 of about 100,307 (296)
机车电传动, 2022 Considering that the entire electric multiple unit (EMU) needs to be withdrawn from service for carrying out preventive maintenance (PM) of the critical equipment, leading to an increase to downtime loss, the concept of replacement repair is proposed in ...
XIONG Lü, LIU Zhilong
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Imperfect Preventive Maintenance Model Study Based On Reliability Limitation
MATEC Web of Conferences, 2016 Effective maintenance is crucial for equipment performance in industry. Imperfect maintenance conform to actual failure process. Taking the dynamic preventive maintenance cost into account, the preventive maintenance model was constructed by using age ...
Zhou Qian, Sun Yufeng
doaj +1 more source
A Periodicity Metric for Assessing Maintenance Strategies [PDF]
, 2009 Organised by: Cranfield UniversityThe maintenance policy in manufacturing systems is devised to reset the machines functionality in an economical fashion in order to keep the products quality within acceptable levels.
ElMaraghy, H. A. +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Journal of Engineering, 2016 The interfaces between the deposition products and concrete are not always well bonded when the electrochemical deposition method (EDM) is adopted to repair the deteriorated concrete.
Qing Chen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Reliability and Availability Analysis of a Two-Unit Cold Standby System with Imperfect Switching
AxiomsThis paper presents a stochastic analysis of a two-unit cold standby system incorporating imperfect switching mechanisms. Each unit operates in one of three states: normal, partial failure, or total failure.
Nariman M. Ragheb +3 more
doaj +1 more source
Journal of Industrial Engineering and Management, 2012 Purpose: Estimate the maintenance efficiency in the Brown-Proschan model with the bathtub failure intensity.Design/methodology/approach: Empirical research through which we propose a framework to establish the characteristics of failure process and its ...
Makram Krit, Abdelwaheb Rebai
doaj +1 more source
Beyond repair foci: DNA double-strand break repair in euchromatic and heterochromatic compartments analyzed by transmission electron microscopy. [PDF]
PLoS ONE, 2012 DNA double-strand breaks (DSBs) generated by ionizing radiation pose a serious threat to the preservation of genetic and epigenetic information. The known importance of local chromatin configuration in DSB repair raises the question of whether breaks in ...
Yvonne Lorat +5 more
doaj +1 more source