Results 41 to 50 of about 1,990,178 (318)

Repairing and meshing imperfect shapes with Delaunay refinement [PDF]

open access: yes2009 SIAM/ACM Joint Conference on Geometric and Physical Modeling, 2009
As a direct consequence of software quirks, designer errors, and representation flaws, often three-dimensional shapes are stored in formats that introduce inconsistencies such as small gaps and overlaps between surface patches. We present a new algorithm that simultaneously repairs imperfect geometry and topology while generating Delaunay meshes of ...
Oleksiy Busaryev   +2 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Is non-homologous end-joining really an inherently error-prone process? [PDF]

open access: yesPLoS Genetics, 2014
DNA double-strand breaks (DSBs) are harmful lesions leading to genomic instability or diversity. Non-homologous end-joining (NHEJ) is a prominent DSB repair pathway, which has long been considered to be error-prone.
Mireille Bétermier   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Reconstruction of a long defect of the median nerve with a free nerve conduit flap

open access: yesArchives of Plastic Surgery, 2020
Upper limb nerve damage is a common condition, and evidence suggests that functional recovery may be limited following peripheral nerve repair in cases of delayed reconstruction or reconstruction of long nerve defects.
Andrea Campodonico   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Fault Tree Analysis for Reliability Analysis of Wind Turbines Considering the Imperfect Repair Effect [PDF]

open access: yes, 2023
Wind turbines are complex and expensive equipment, requiring high reliability and low maintenance costs. However, most of the existing fault tree analysis (FTA) methods for reliability analysis of wind turbines assume that the repair of wind turbines can
Rana, Zuraiz   +7 more
core   +1 more source

Optimal number of imperfect repairs for deteriorating systems [PDF]

open access: yesInternational Journal of Industrial Engineering and Production Research
A periodic maintenance policy through either an imperfect repair or replacement is proposed for a repairable system. It is assumed that the system is subject to an inverse Gaussian degradation process.
Khatereh Rajinia, Mostafa Razmkhah
doaj  

Models of Imperfect Repair

open access: yes, 2012
Repair is a type of maintenance carried out on an item after it fails. A failure may occur any time, hence the times to repair cannot be pre-specified. Methods used to model times to failures are normally stochastic processes such as the renewal process and the homogeneous Poisson process, depending on the effectiveness of a repair.
Luo, M., Wu, S., Scarf, P.
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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