Results 51 to 60 of about 26,553 (309)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Dealing with Imperfection Sensitivity of Composite Structures Prone to Buckling

, 2012
The Space industry demands for lighter and cheaper launcher transport systems. Structural weight reduction by exploitation of structural reserves in composite launcher structures contributes to this aim, however, it requires accurate, fast and ...
Falk Odermann, Degenhardt, Richard, Zimmermann, Rolf, F.C. de, Araujo, Francisco Celio, Alexander Kling, Rolf Zimmermann, Kling, Alexander, Odermann, Falk, Richard Degenhardt, de Araújo, F.C.   +10 more
core   +1 more source

Performance Investigation of Metaheuristic Niched-Pareto Genetic Algorithm for Imperfection Assessment of Structures [PDF]

Journal of Structural and Construction Engineering, 2019
Structures depending on the type of their application are subject to different types of loading, such as wind, earthquake and explosion loads. On the other hand, in order to increase the useful lifetime of the structures, optimal operating conditions ...
Milad Jahangiri, Behrouz Ahmadi Nedushan
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Geometric Imperfection Simulations in Cee-Shape Cold-Formed Steel Members Based on Newly Developed Machine-Vision Inspection Techniques

Buildings, 2023
This paper insightfully studies geometric imperfection simulations of cee-section CFS members from laser-based measurements. A machine-vision imperfection inspection technique is first developed where an algorithm is implemented to automate imperfection ...
Hanbo Guan, Xi Zhao, Pengfei Du, Xiaoyan Sun   +3 more
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Affirmative Imperfection Rhetoric and Aesthetics

, 2021
Ideally, spellcheckers, navigation systems, photo filters, and other digital technologies allow us to perfect our everyday lives with each day. In practice, they not only boast bugs – but their ‘politics of perfection’ (Hale 2016) also evokes a fierce ...
Ellen Rutten, Rutten, E.
core   +1 more source

Buckling and postbuckling of carbon nanotube-reinforced composite cylindrical panels subjected to axial compression in thermal environments

Vietnam Journal of Mechanics, 2018
This paper presents an analytical investigation on the buckling and postbuckling behavior of thin composite cylindrical panels reinforced by single walled carbon nanotubes (SWCNTs), exposed to thermal environments and subjected to uniform axial ...
Le Thi Nhu Trang, Hoang Van Tung
doaj   +1 more source

Influence of Imperfect Position of a Striker and Input Bar on Wave Propagation in a Split Hopkinson Pressure Bar (SHPB) Setup with a Pulse-Shape Technique

Applied Sciences, 2020
The effect of using a pulse shaper technique, such as rounding a striker or applying a pulse shaper on the signals recorded with the split Hopkinson pressure bar (SHPB) technique, when the striker and the input bar are in an imperfect position, was ...
Robert Panowicz, Marcin Konarzewski
doaj   +1 more source