Results 111 to 120 of about 26,368 (244)

Effect of retention design of artificial teeth and implant-supported titanium CAD-CAM structures on fracture resistance [PDF]

open access: yes, 2016
Background: For implant-supported hybrid prostheses, high mastication forces and reduced acrylic resin thickness over a metal substructure often cause failures arising from tooth or resin fractures.
Ladetzki, Kristin   +3 more
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Stress distribution by parafunctional loading on tooth–implant, implant–implant, and tooth–tooth-supported prosthesis: A comparative three-dimensional finite element analysis

open access: yesThe Journal of Indian Prosthodontic Society
Aim: The study’s objective was to evaluate the stress distribution in tooth-implant, implant-implant, and tooth-tooth supported prostheses under parafunctional loading in axial and oblique directions employing a 3D finite element analysis in the ...
P Ambili Ravindran   +5 more
doaj   +1 more source

DIGITAL TRANSFORMATION OF THE IMPLANT SUPPORTED PROSTHODONTIC REHABILITATION

open access: diamond, 2021
Роман Розов   +1 more
openalex   +1 more source

Validation of an experimental polyurethane model for biomechanical studies on implant supported prosthesis - tension tests [PDF]

open access: yes, 2011
OBJECTIVES: The complexity and heterogeneity of human bone, as well as ethical issues, frequently hinder the development of clinical trials. The purpose of this in vitro study was to determine the modulus of elasticity of a polyurethane isotropic ...
FERREIRA, Paulo Martins   +4 more
core   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Penanggulangan Komplikasi dalam Perawatan Restorasi Implan Tulang

open access: yesJournal of Dentistry Indonesia, 2015
Clinical complications of endosseous implants are the effects of mal-treatments including patient selection, treatment planning, clinical execution and patient cooperation.
Suhandi Sidjaja
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Mechanical Evaluation of Two Different Zirconia-Reinforced Lithium Silicate Ceramics: A Finite Element Analysis

open access: yesCurrent Research in Dental Sciences
Objective: The aim of the study is to evaluate the stress distribution of zirconia-reinforced lithium silicate all-ceramic fixed partial dentures under occlusal loading; in terms of material, restoration, and supporting type.Methods: Six different models
Hüseyin Botsalı   +3 more
doaj   +1 more source

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