Results 51 to 60 of about 483,999 (304)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Ruolo della stimolazione bimodale nello sviluppo delle abilità percettivo-uditive nei bambini con impianto cocleare monolaterale [PDF]

Acta Otorhinolaryngologica Italica, 2015
Il presente studio prospettico randomizzato ha lo scopo di valutare le differenze che emergono tra una stimolazione bimodale e una elettrica monolaterale nei bambini sordi, in particolare in termini di sviluppo delle abilità percettivo-uditive ...
P. MARSELLA, S. GIANNANTONIO, A. SCORPECCI, F. PIANESI, M. MICARDI, A. RESCA   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Immunological aspects of implantation and implantation failure [PDF]

Human Reproduction, 1999
The human endometrium contains a significant proportion of leukocytes (8-35% of all cells), the absolute numbers and proportions varying during both the menstrual cycle and early in pregnancy. T cells, macrophages and a population of phenotypically unusual large granular lymphocytes (LGL) are commonly present, although B cells are absent.
P M, Johnson, S E, Christmas, G S, Vince
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Staphylococcal response to daptomycin in implant-associated infections [PDF]

, 2011
The use of medical devices carries the risk of infection. Due to the development of multi-resistant bacteria, missing microcirculation, and biofilm embedded bacteria these implant-associated infections are difficult to treat.
John, Anne-Kathrin
core   +1 more source

Radiographic Imaging in Implant Dentistry

, 2023
Radiographic imaging is key in all phases of dental implant therapy, i.e., diagnosis, planning and assessment of treatment, and long-term monitoring, both in terms of clinical practice and in implant research.
Stavropoulos, Andreas,, Wenzel, Ann,, Beck, Florian,, Cattaneo, Paolo,, Bertl, Kristina,   +4 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Influence of abutment material on peri-implant clinical parameters: a prospective study

Brazilian Dental Science, 2014
Objective: This study evaluated the peri-implant clinical parameters of zirconia versus metallic abutments for standardized custom-made implantsupported single-tooth restorations.
Fabiano Cortez Zanardo, José Della Pasqua Neto, Luiz Henrique Alves Madeira, Jamil Awad Shibli, Keize Távora Barbosa, José Augusto Rodrigues, Alessandra Cassoni   +6 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source