Results 61 to 70 of about 483,999 (304)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

PromBERA: A preoperative eABR: An update

Current Directions in Biomedical Engineering, 2018
Prior to cochlear implantation, audiological tests are performed to determine candidacy in subjects with a hearing loss. This is usually done by measuring the acoustic auditory brainstem response (ABR).
Polterauer Daniel, Neuling Maike, Müller Joachim, Hempel John-Martin, Mandruzzato Giacomo, Polak Marek   +5 more
doaj   +1 more source

Factors influencing the sinus membrane thickness in edentulous regions: a cone-beam computed tomography study

International Journal of Implant Dentistry, 2021
Background During implant treatment in the maxillary molar area, maxillary sinus floor augmentation is often performed to ameliorate the reduced alveolar bone height attributable to bone remodeling and pneumatization-induced expansion of the maxillary ...
Motohiro Munakata, Kikue Yamaguchi, Daisuke Sato, Naoko Yajima, Noriko Tachikawa   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Improved tactile speech perception using audio-to-tactile sensory substitution with formant frequency focusing

Scientific Reports
Haptic hearing aids, which provide speech information through tactile stimulation, could substantially improve outcomes for both cochlear implant users and for those unable to access cochlear implants.
Mark D. Fletcher, Esma Akis, Carl A. Verschuur, Samuel W. Perry   +3 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Computer guided dental implant placement

, 2020
Discribe conventional and computer guided implant surgery. Different types of template according to supporting type and design concept. Way of fabrication of each template.
Sang Jun, An
core  

A technique for atraumatic extraction of teeth before immediate implant placement using implant drills

, 2009
Purpose: The purpose of this article is to present a minimally invasive technique using the implant drills to help extract teeth before the insertion of immediate ...
Aktaş, İrem, Aybar, Buket, Emes, Yusuf, Yalçın, Serhat, Atalay, Belir, Kaya Birinkulu, Gül, kaya, Gul, Yalcin, Serhat   +7 more
core   +1 more source

Ossteointegration Of A 26-Year Machined Implant: A Histological Report

International Dental Journal
Introduction: Machined dental implants are the first generation of dental implant. In previous studies, surface roughness has been proposed to have a positive effect on ossteointegration, and machined surface interfered with bone interlocking and delayed
Yuanjing Wang, Yu Xie, Huihui Zhang
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source