Results 111 to 120 of about 1,620,931 (303)

Analysis of technical complications and risk factors for failure of combined tooth-implant-supported fixed dental prostheses

, 2020
BACKGROUND: The oral rehabilitation with fixed restorations supported by the combination of teeth and dental implants has been advocated in some cases. PURPOSE: To assess the clinical outcomes of these prostheses.
Bruno Ramos Chrcanovic, Chrcanovic, Bruno Ramos, Kisch, Jenö, Christel Larsson, Jenö Kisch, Kisch, Jenö,, Larsson, Christel,, Larsson, Christel, Chrcanovic, Bruno Ramos,   +8 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Implant failure after ankle arthrodesis versus total ankle arthroplasty: a matched- cohort study

Journal of the Foot & Ankle
Objective: To compare the risk of implant failure between ankle arthrodesis and total ankle arthroplasty using propensity score matching and time-to-event analysis.
Cláudia Diniz Freitas, Natália Helena Tau, Deivid Ramos dos Santos, Eduardo Cezar Silva dos Santos   +3 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Implications of considering peri‐implant bone loss a disease, a narrative review

, 2022
BACKGROUND: Peri‐implantitis has been suggested to cause significant increasing proportions of implant failure with increasing time. PURPOSE: To assess whether implant failure rates in long term studies are matching the supposed high prevalence of peri ...
Amengual‐Peñafiel, Luis, Coli, Pierluigi,, Tengvall, Pentti, Tengvall, Pentti,, Amengual-Penafiel, L., Coli, Pierluigi, Pierluigi Coli, Georgios Kotsakis, Kotsakis, Georgios,, Cochran, D. L., Luis Amengual‐Peñafiel, Cochran, David L., Albrektsson, Tomas, Kotsakis, Georgios, David L. Cochran, Albrektsson, Tomas,, Tomas Albrektsson, Pentti Tengvall   +17 more
core   +1 more source

Dentists’ Perspectives on Defining Failure in Implant-Prosthodontic Therapy: A Cross-Sectional Study

Applied Sciences
Aim: to investigate the criteria to define implant–prosthodontic therapy failure for dentists in Croatia. Methods: We conducted a cross-sectional study using an online questionnaire among dentists in Croatia.
Mare Kovic, Ajka Pribisalic, Josko Viskic, Eva Bilandzic, Anamarija Tokic, Marija Ana Perko, Tina Poklepovic Pericic   +6 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Evaluation of Failure Rate for Cortical Dental Implants Placed in the Mandibular Anterior Region: A Systematic Review [PDF]

Journal of Clinical and Diagnostic Research
Introduction: To enhance the success of dental implants, it is crucial to understand the factors contributing to implant failure. Practitioners should carefully evaluate the relevance and impact of critical risk factors associated with the mandibular ...
Srishty Goyal, Dhirendra Kumar Singh, Kumari Lucy Bhola, Jalaluddin Mohammad   +3 more
doaj   +1 more source

Molecular aspects of implantation failure

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2012
Despite expanding global experience with advanced reproductive technologies, the majority of IVF attempts do not result in a successful pregnancy, foremost as a result of implantation failure. The process of embryo implantation, a remarkably dynamic and precisely controlled molecular and cellular event, appears inefficient in humans and is poorly ...
Koot, Y.E.M., Teklenburg, G., Salker, M.S., Brosens, J.J., Macklon, N.S.   +4 more
openaire   +3 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source