Results 51 to 60 of about 4,216,321 (282)

How does facilitation in healthcare work? Using mechanism mapping to illuminate the black box of a meta-implementation strategy

Implementation Science Communications, 2023
Background Healthcare facilitation, an implementation strategy designed to improve the uptake of effective clinical innovations in routine practice, has produced promising yet mixed results in randomized implementation trials and has not been fully ...
Amy M. Kilbourne, Elvin Geng, Ingrid Eshun-Wilson, Shannon Sweeney, Donna Shelley, Deborah J. Cohen, JoAnn E. Kirchner, Maria E. Fernandez, Michael L. Parchman   +8 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

A System To Facilitate Telematic Implementation

IFAC Proceedings Volumes, 2001
Abstract In the interest of promoting online robotics education, this paper presents a system to allow research institutions to easily make robots available on the internet. The system is based on Java and provides a simple, yet complete package to handle network communication, user management, serial device, and identification activities.
John Ogness, Klaus Schilling, Hubert Roth   +2 more
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Evaluating remote facilitation intensity for multi-national translation of nurse-initiated stroke protocols (QASC Australasia): a protocol for a cluster randomised controlled trial

Implementation Science, 2023
Background Facilitated implementation of nurse-initiated protocols to manage fever, hyperglycaemia (sugar) and swallowing difficulties (FeSS Protocols) in 19 Australian stroke units resulted in reduced death and dependency for stroke patients. However, a
O. Fasugba, S. Dale, E. McInnes, D. A. Cadilhac, M. Noetel, K. Coughlan, B. McElduff, J. Kim, T. Langley, N. W. Cheung, K. Hill, V. Pollnow, K. Page, E. Sanjuan Menendez, E. Neal, S. Griffith, L. J. Christie, J. Slark, A. Ranta, C. Levi, J. M. Grimshaw, S. Middleton   +21 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Cluster-randomized implementation trial of two facilitation strategies to implement a novel information and communications technology at the Veterans Health Administration

Implementation Science
Background Information and communication technologies (ICTs) improve quality and efficiency of healthcare, but effective practices for implementing new ICTs are unknown.
Chelsea Leonard, Evan Carey, Ariel Holstein, P. Michael Ho, Jeffrey T. Heckman   +4 more
doaj   +1 more source

Navigating the facilitation journey: a qualitative, longitudinal evaluation of ‘Eat Walk Engage’ novice and experienced facilitators

BMC Health Services Research, 2023
Background The Promoting Action on Research Implementation in Health Services (PARIHS) and integrated-PARIHS (i-PARIHS) frameworks position facilitation as an overarching strategy to enable implementation.
Gillian Harvey, Sarah Collyer, Prue McRae, Sally E. Barrimore, Camey Demmitt, Karen Lee-Steere, Bernadette Nolan, Alison M. Mudge   +7 more
doaj   +1 more source