Results 51 to 60 of about 591,472 (262)

Theory-based development of a tailored implementation strategy tool to promote Early Essential Newborn Care practice: A protocol

Women and Children Nursing
Objectives: We aimed to develop an implementation tool that could help healthcare professionals identify modifiable factors and develop tailored implementation strategies to promote the implementation of Early Essential Newborn Care (EENC) under the ...
Hongxiao He, Na Wang, Jie Lu, Jiahe Li, Junying Li, Hong Lu, Xiu Zhu   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Integrating thrombolysis into routine stroke care in a Ghanaian tertiary hospital, using the implementation research logic model (IRLM) as a guiding framework

Journal of Stroke and Cerebrovascular Diseases
Background: Despite bearing the brunt of the global burden of post-stroke disability, cost-effective acute treatments such as stroke thrombolysis remain significantly underutilized in Low- and Middle-Income Countries.
Priscilla Abrafi Opare-Addo, Fred Stephen Sarfo, Chris Oppong, Sheila Adamu, Ishaak Ahmed Yussif, Manolo Agbenorku, Kwasi Ankomah, Kwasi Adjepong Twum, Emmanuel Boadi Attafuah, Akosua Afriyie-Ansah, John Emmanuel Oppong Mensah, Sommik Miilon Duut, Minas Aikins, Alfred Opata, Benedict Kusi Ampofo, Yaa Bema Sarkodie Amankwah, Khabib Abdulai Baba, Serwaa Asare-Bediako, Eno Akua Afriyie Biney, Rexford Adu Gyamfi, Vida Obese, Hanson Ababio, Ama Kwakyewaa Bedu-Addo, Moses Siaw-Frimpong, Alice Oppong Damprane, Philip Kankam Boadu, Martha Owusu, Afia Bempomaa Opoku-Boateng, Ibrahim Kasanga, Maxwell Nyenaah, Bernice Agyeman Prempeh, Daniel Osei Kwame, José Biller   +32 more
doaj   +1 more source

ANALISIS FAKTOR PENDORONG REALISASI MANFAAT IMPLEMENTASI ERP DI PERUSAHAAN INDONESIA

J@ti Undip: Jurnal Teknik Industri, 2017
Pengelolaan implementasi ERP pada fase post project yaitu fase ketika ERP telah digunakan secara integral dalam perusahaan, menentukan terealisasinya manfaat dari implementasi ERP, karenanya terkait pengelolaan pada fase post project ini dibutuhkan ...
Iqbal Yulizar M., Rajesri Govindaraju
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Compatibility Implementation Plan for Xi’an Metro Line 2 Phase Ⅰ and Phase Ⅱ Project Signaling Systems

Chengshi guidao jiaotong yanjiu
[Objective] The signaling system for Xi’an Metro Line 2 Phase Ⅰ project (hereinafter referred to as Line 2) utilizes an imported system, while Phase Ⅱ adopts a domestically developed system.
SUN Hui, REN Yaping, LIANG Bo
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Agile nudge implementation to improve minority recruitment in community-based research

Frontiers in Health Services
BackgroundRecruiting underrepresented populations into community-based research remains a persistent challenge in the United States, driven in part by inequities, historical mistrust, and institutional barriers that limit access to and engagement in ...
Olanrewaju Onigbogi, Malaz Boustani, Ali Ajrouch, Kebba Kah, Kolawole Okuyemi, Diana Summanwar   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source