Results 61 to 70 of about 669,720 (312)

Phase transition behaviour in constraint satisfaction problems [PDF]

open access: yes, 1997
Many problems in artificial intelligence and computer science can be formulated as constraint satisfaction problems (CSPs). A CSP consists of a set of variables among which a set of constraints are imposed, with a solution corresponding to an assignment ...
Stuart Alexander Grant   +1 more
core  

A Bayesian approach for dose-escalation in a phase I clinical trial incorporating pharmacodynamic endpoints . [PDF]

open access: yes, 2007
Bayesian decision procedures have already been proposed for and implemented in phase I dose-escalation studies in healthy volunteers. The procedures have been based on pharmacokinetic responses reflecting the concentration of the drug in blood plasma and
Hampson, Lisa   +8 more
core   +1 more source

Efficient implementation of 90° phase shifter in FPGA

open access: yesEURASIP Journal on Advances in Signal Processing, 2011
In this article, we present an efficient way of implementing 90° phase shifter using Hilbert transformer with canonic signed digit (CSD) coefficients in FPGA.
Duraiswamy Punithavathi   +2 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Low-complexity high-performance GFSK receiver with carrier frequency offset correction

open access: yes, 2004
This paper presents an implementation of a GFSK receiver based on matched filtering of a sequence of K successive bits. This enables improved detection and superior BER performance but requires 2K matched filters of considerable complexity.
Weiss, Stephan   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

FPGA Implementation of a General Space Vector Approach on a 6-Leg Voltage Source Inverter [PDF]

open access: yes, 2011
A general algorithm of a Space Vector approach is implemented on a 6-leg VSI controlling a PM synchronous machine with three independent phases. In this last case, the necessity of controlling the zero-sequence current motivates the choice of a special ...
COLAS, Frédéric   +13 more
core   +1 more source

Theory-based development of a tailored implementation strategy tool to promote Early Essential Newborn Care practice: A protocol

open access: yesWomen and Children Nursing
Objectives: We aimed to develop an implementation tool that could help healthcare professionals identify modifiable factors and develop tailored implementation strategies to promote the implementation of Early Essential Newborn Care (EENC) under the ...
Hongxiao He   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Integrating thrombolysis into routine stroke care in a Ghanaian tertiary hospital, using the implementation research logic model (IRLM) as a guiding framework

open access: yesJournal of Stroke and Cerebrovascular Diseases
Background: Despite bearing the brunt of the global burden of post-stroke disability, cost-effective acute treatments such as stroke thrombolysis remain significantly underutilized in Low- and Middle-Income Countries.
Priscilla Abrafi Opare-Addo   +32 more
doaj   +1 more source

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