Results 61 to 70 of about 2,649,115 (298)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Full-field stress analysis by holographic phase-stepping implementation of the photoelastic-coating method [PDF]

open access: yes, 2012
In this paper, we describe a system for polariscopic and holographic phase-shifting implementation of the photoelastic-coating method for a full-field stress analysis.
Degrieck, Augustijn   +5 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Efficient implementation of 90° phase shifter in FPGA

open access: yesEURASIP Journal on Advances in Signal Processing, 2011
In this article, we present an efficient way of implementing 90° phase shifter using Hilbert transformer with canonic signed digit (CSD) coefficients in FPGA.
Duraiswamy Punithavathi   +2 more
doaj  

Theory-based development of a tailored implementation strategy tool to promote Early Essential Newborn Care practice: A protocol

open access: yesWomen and Children Nursing
Objectives: We aimed to develop an implementation tool that could help healthcare professionals identify modifiable factors and develop tailored implementation strategies to promote the implementation of Early Essential Newborn Care (EENC) under the ...
Hongxiao He   +6 more
doaj   +1 more source

Pharmacist-directed vancomycin therapeutic drug monitoring in pediatric patients: a collaborative-practice model

open access: yesJournal of Pharmaceutical Policy and Practice, 2021
Background Therapeutic drug monitoring (TDM) of Vancomycin (VCM) is required to prevent inappropriate dosage-associated bacterial resistance, therapeutic failure, and toxicities in pediatrics.
Kashif Hussain   +3 more
doaj   +1 more source

Implementing Arbitrary Phase Gates with Ising Anyons [PDF]

open access: yesPhysical Review Letters, 2010
Ising-type non-Abelian anyons are likely to occur in a number of physical systems, including quantum Hall systems, where recent experiments support their existence. In general, non-Abelian anyons may be utilized to provide a topologically error-protected medium for quantum information processing. However, the topologically protected operations that may
Bonderson, Parsa   +3 more
openaire   +3 more sources

Design of Predictive Controllers by Dynamic Programming and Neural Networks [PDF]

open access: yes, 2003
This paper proposes a method for the design of predictive controllers for nonlinear systems. The method consists of two phases, a solution phase and a learning phase.
Nagurka, Mark L., Yen, Chen-Wen
core   +1 more source

Plasmonic Superlens Imaging Enhanced by Incoherent Active Convolved Illumination

open access: yes, 2018
We introduce a loss compensation method to increase the resolution of near-field imaging with a plasmonic superlens that relies on the convolution of a high spatial frequency passband function with the object. Implementation with incoherent light removes
Adams, Wyatt   +2 more
core   +1 more source

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