Results 81 to 90 of about 555,304 (261)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Protocol for iSISTAQUIT: Implementation phase of the supporting indigenous smokers to assist quitting project. [PDF]

open access: yesPLoS One, 2022
Gould Judean GS   +11 more
europepmc   +1 more source

Design & Implementation of High Switching & Low Phase Noise Frequency Synthesizer

open access: yesAl-Khawarizmi Engineering Journal, 2006
This research describes the design & implementation of frequency synthesizer using single loop Phase lock loop with the following specifications: Frequency range (1.5 – 2.75) GHz,Step size (1 MHz), Switching time 36.4 µs, & phase noise @10 kHz = -92dBc &
Ali M. N. Hassan
doaj  

Phase III: Implementation and Operation of the repository [PDF]

open access: yes, 1998
The metadata catalog was brought online for public access May 14, 1998. Since then dozens of users have registered and began to access the system. The system was demonstrated at the AAPG annual meeting in Salt Lake City and the EAGE (European Association of Geoscientists and Engineers) annual meeting in Leipzig, Germany.
openaire   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

'A priori' external contextual factors and relationships with process indicators: a mixed methods study of the pre-implementation phase of 'Communities in Charge of Alcohol'. [PDF]

open access: yesBMC Public Health, 2022
Burns EJ   +9 more
europepmc   +1 more source

Developing and testing a produce prescription implementation blueprint to improve food security in a clinical setting: a pilot study protocol

open access: yesPilot and Feasibility Studies
Background Food insecurity is common in the United States, especially in Rhode Island, where it affects up to 33% of residents. Food insecurity is associated with adverse health outcomes and disproportionally affects people from minoritized backgrounds ...
Hannah E. Frank   +10 more
doaj   +1 more source

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