Results 91 to 100 of about 7,515,929 (289)

Kenya Community Health Strategy 2020-2025

open access: yes, 2020
The Kenya Community Health Strategy 2020 – 2025 (KCHS 2020 – 2025) was developed to build on the Community Health Strategy 2014 – 2019. The development of the KCHS 2020 – 2025 is based on the lessons learnt from the implementation of the Community Health

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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Evolution de la stratégie de modélisation au sein du service prévision des crues Vilaine et Côtiers Bretons et conséquences sur la production de la vigilance

open access: yesLHB Hydroscience Journal
Le Service Prévision des Crues Vilaine et Côtiers Bretons (SPC VCB) est responsable de la vigilance crues sur les cours d’eau à enjeux de la région Bretagne depuis 2005. Depuis presque 20 ans, les attentes des gestionnaires de crise comme du grand public
Robin Treilles   +7 more
doaj   +1 more source

A Full Characterization of Nash Implementation with Strategy Space Reduction [PDF]

open access: yes
Noting that a full characterization of Nash-implementation is given using a canonical-mechanism and Maskin’s theorem (Maskin, 1999) is shown using a mechanism with Saijo’s type of strategy space reduction (Saijo, 1988), this paper fully characterizes the
Yoshihara, Naoki, Lombardi, Michele
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Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A Model for Identifying and Analyzing of Strategy Implementation Barriers [PDF]

open access: yesمطالعات مدیریت راهبردی, 2016
This research designs a model for Identifying and Analyzing of Strategy Implementation Barriers in Saman Bank. At first, the theoretical principals and concepts are reviewed and then measuring indicators of each index and dimension are derived by the ...
Mohammad Ali Babayi Zekilaki   +3 more
doaj  

Bayesian and Dominant Strategy Implementation Revisited [PDF]

open access: yes
We consider a standard social choice environment with linear utility and one-dimensional types. We show by counterexample that, when there are at least three physical alternatives, Bayes-Nash Incentive Compatibility (BIC) and Dominant Strategy Incentive ...
Benny Moldovanu   +2 more
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National E-Waste Management Strategy 2019-2024 [PDF]

open access: yes, 2019
The National E-waste Management Strategy is a five-year plan covering the period 2019/20 to 2023/24. The E-waste Strategy has five thematic areas aimed at resource mobilization for proper E-waste management, raising awareness, strengthening Kenya’s E ...

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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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