Results 71 to 80 of about 7,515,929 (289)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
THE IMPACT OF STRATEGY ON ICT PROJECTS
Strategic planning processes are oriented towards the selection of objectives and product/market choices by senior management. From this viewpoint strategic planning provides a mechanism for setting and reviewing objectives, focusing on choices of long ...
G. Udechukwu Ojiako +2 more
doaj
IMPLEMENTATION STRATEGY OF MULTICULTURAL EDUCATION BASED ON ISLAMIC VALUES AT SMP SUMBARRANG
Multicultural education plays a vital role in promoting moderate and inclusive Islamic values, particularly in pluralistic school environments. This study explores the implementation strategies of multicultural education based on Islamic values at SMP ...
Azis, Hilmi Ismail, Ismail
doaj +1 more source
The challenges of implementing strategy
Strategy implementation is a hot topic today. Managers spend billions of dollars on consulting and training in the hope to create brilliant strategies. But all too often brilliant strategies do not translate into brilliant performance.
Verweire, Kurt
core
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
ObjectiveDeep coalbed methane (CBM; burial depths: > 1500 m) in China holds considerable resource potential. As a strategic clean energy, deep CBM is exhibiting increasingly high value of exploitation and utilization.
Xinjun CHEN +5 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Progress report on implementation aspects of the Thames River Basin water management study [PDF]
This progress report identifies the preliminary stance adopted by the Thames River Implementation Committee towards the 29 recommendations contained in the 1975 Thames River Basin Water Management Study and outlines the activities carried out by the ...
Thames River Implementation Committee
core +1 more source
This strategy is founded on intelligence from global and regional trends in bioenergy production and consumption and an understanding of the local bioenergy industry status.
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source

