Results 61 to 70 of about 8,531 (254)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Something Old, Something New: Excursions into Finnish Sacrifical Carins
Temenos, 2008 The article approaches the archaeological phenomenon known in Finland as 'sacrificial cairns' by examining the scholarly history and by placing these cairns in the context of the recent theoretical discussion concerning the essence of ritual and secular ...
TIMO MUHONEN
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Importance of Community Forestry Funds for Rural Development in Nepal
Resources, 2019 Nepal’s Community Forestry (CF) process has implied the devolution of powers to collect, retain, and redistribute forest revenue from community forests products.
Puspa K.C. Bhandari +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Shakespeare’s Poetics of Impurity: Spots, Stains, and Slime
Etudes Epistémè, 2018 Spots, stains and smears keep recurring in Shakespeare’s plays and poems, where they often appear as the marks of sin, evil and violence. While this is undoubtedly the case in a number of occurrences, I argue here that these polluted sites of exploration
Sophie Chiari
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DOT: Gene-set analysis by combining decorrelated association statistics.
PLoS Computational Biology, 2020 Historically, the majority of statistical association methods have been designed assuming availability of SNP-level information. However, modern genetic and sequencing data present new challenges to access and sharing of genotype-phenotype datasets ...
Olga A Vsevolozhskaya +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
From hauntology to a new animism? Nature and culture in Heinz Kimmerle’s intercultural philosophy
The Journal for Transdisciplinary Research in Southern Africa, 2007 Derrida has proposed a new spectrology in an attempt to deal with the ghost of Marx. Kimmerle shows that Marx has forgotten nature, and enquires about Derrida’s forgetting Marx’s forgetting.
Murray Hofmeyr
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