Results 51 to 60 of about 573,689 (294)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Analysis of foreign direct investment in the Czech Republic
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2011 The foreign direct investments are joined with the process of world globalisation. Foreign direct investments are carried out especially by multinational companies.
Marcela Domesová
doaj +1 more source
Features of conducting a forensic commodity examination of furniture products
Bulletin of Kharkiv National University of Internal Affairs, 2023 The scientific article defines the methodological aspects of conducting a forensic commodity examination of furniture products, outlines the theoretical and practical problems of commodity research of furniture products, reveals the commodity ...
M. V. Hаrbuz, L. Yu. Ulybіnа
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Made in China, Sold in Norway: Local Labor Market Effects of an Import Shock
Social Science Research Network, 2015 We analyze whether regional labor markets are affected by exposure to import competition from China. We find negative employment effects for low-skilled workers, and observe that low-skilled workers tend to be pushed into unemployment or leave the labor ...
Ragnhild Balsvik +2 more
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Can Innovation Help U.S. Manufacturing Firms Escape Import Competition from China?
Journal of Finance, 2015 We study whether R&D-intensive firms are more resilient to trade shocks. We correct for the endogeneity of R&D using tax-induced changes to the cost of R&D.
J. Hombert, Adrien Matray
semanticscholar +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
AntioxidantsThe increasing popularity of herbal supplements emphasizes the need of scientific data regarding their health benefits and possible toxicological concerns.
Lucian Albulescu +4 more
doaj +1 more source