Results 71 to 80 of about 5,538,294 (301)
Cytosolic Hsp70 and co-chaperones constitute a novel system for tRNA import into the nucleus
eLife, 2015 tRNAs are unique among various RNAs in that they shuttle between the nucleus and the cytoplasm, and their localization is regulated by nutrient conditions.
Akira Takano +4 more
doaj +1 more source
Phosphorylation regulates the assembly of chloroplast import machinery [PDF]
, 2008 Chloroplast function depends on the translocation of cytosolically synthesized precursor proteins into the organelle. The recognition and transfer of most precursor proteins across the outer membrane depend on a membrane inserted complex.
Oreb, Igor-Mislav +7 more
core +2 more sources
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
An aggregate import demand function for Australia: a cointegration approach [PDF]
This paper investigates the relationship among quantity of imports, relative import prices and real GDP in the aggregate import demand function for Australia during the period 1959Q3Ã’2006Q3.
Riaz Shareef, Vu Tran
core
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Biology Open, 2016 Mitochondrial function is tied to the nucleus, in that hundreds of proteins encoded by nuclear genes must be imported into mitochondria. While post-translational import is fairly well understood, emerging evidence supports that mitochondrial site ...
Aditya Sen, Rachel T. Cox
doaj +1 more source
An aggregate import demand function for Turkey: a cointegration analysis [PDF]
This paper estimates an aggregate import demand function for Turkey during the period 1994:1-2003:12. In our empirical analysis of the aggregate import demand function for Turkey, cointegration and error correction modeling approaches have been used ...
Kalyoncu, Huseyin
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Estimated Import Demand Function for Pakistan: A Disaggregated Analysis
JISR Management and Social Sciences & Economics, 2015 The theme of the study was to estimate the elasticity of aggregated and selected disaggregated import demand function with relative prices and income for Pakistan from 1982 to 2011 on annual data.
Imran Ullah Khan Marwat
doaj