Results 101 to 110 of about 34,230,496 (248)

Deep Learning Pose Estimation for Phenotyping of Co-Occurring Hyperkinetic Movement Disorders. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Cif L, Demailly D, Horvàth GA, Ortigoza Escobar JD, Dorison N, Castro Jiménez M, Hubsch CA, Wirth T, Hariz GM, Huby S, Dornadic M, Souei Z, Mushhood Ur Rehman M, Hemm S, Boulaymen M, Moraud EM, Bloch J, Vasques X.   +17 more
europepmc   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Labor Mobility across Borders and Macroeconomic Outcomes: Dynamic Evidence from Pakistan

Journal of Business and Social Review in Emerging Economies
Purpose: This study investigates the relationship between international labor mobility and Pakistan’s macroeconomic performance by examining the influence of push and pull factors, along with the mediating roles of remittances and globalization ...
Khizra Sardar, Zinas Aisha, Hina Ali
doaj   +1 more source

Performance based interactive analysis

, 2011
This paper re-approaches structural engineering through an interactive perspective by introducing a series of tools that combine parametric design with structural analysis, thus achieving a synergy between the architectural shape and its structural ...
Richens, P., Shepherd, P., Georgiou, O.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Forecasting Tuberculosis Incidence in Somalia: A Comparative Analysis of Single and Hybrid Time‐Series Models

Health Science Reports
Background Tuberculosis (TB) remains a significant public health challenge, necessitating accurate forecasting methodologies to support effective control and prevention strategies. This paper explores the application and comparative performance of single
Hana Mahdi Dahir, Ayan Husein Korse, Farduus Ibrahim Mohamed, Saralees Nadarajah, Mohamed Said Hassan   +4 more
doaj   +1 more source

Exchange Rate Prediction Under Data Volatility: A Comparison Of Deep Learning Techniques

Journal of Metaverse
This Accurate prediction of exchange rates is of critical importance for economic policy related decision making. This study employs a deep learning based framework to model exchange rate dynamics by explicitly accounting for the inherently nonlinear ...
Filiz Erataş Sönmez, Şule Öztürk Birim   +1 more
doaj   +1 more source

Global Buildings Performance Network (GBPN)

, 2015
The GBPN’s goal is to contribute to the building sector achieving its full energy savings and CO2mitigation potential of more than 2.1 Gt by 2030. The GBPN was founded in 2010 with the mandate to advance knowledge and expertise globally on building ...
Global Buildings Performance Network
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source