Results 101 to 110 of about 2,663,721 (268)

Deep Importance Sampling

open access: yes, 2020
We present a generic path-dependent importance sampling algorithm where the Girsanov induced change of probability on the path space is represented by a sequence of neural networks taking the past of the trajectory as an input. At each learning step, the neural networks' parameters are trained so as to reduce the variance of the Monte Carlo estimator ...
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

ANÁLISIS BAYESIANO DE ESTABILIDAD FENOTIPICA USANDO A PRIORI DE JEFFREYS BAYESIAN PHENOTYPIC STABILITY ANALYSIS USING JEFFREYS’S PRIOR

open access: yesRevista Facultad Nacional de Agronomía Medellín, 2006
Uno de los métodos utilizados para evaluar estabilidad fenotípica es el propuesto por Shukla, el cual calcula la varianza de los genotipos dentro de la interacción genotipo por ambiente, para lo cual se hace uso de la estimación de los componentes de ...
José Miguel Cotes Torres   +1 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Group Importance Sampling for Particle Filtering and MCMC

open access: yes, 2018
Bayesian methods and their implementations by means of sophisticated Monte Carlo techniques have become very popular in signal processing over the last years.
Camps-Valls, G., Elvira, V., Martino, L.
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Improving MCMC Using Efficient Importance Sampling [PDF]

open access: yes
This paper develops a systematic Markov Chain Monte Carlo (MCMC) framework based upon Efficient Importance Sampling (EIS) which can be used for the analysis of a wide range of econometric models involving integrals without an analytical solution.
Liesenfeld, Roman   +1 more
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Inference for Two-Parameter Birnbaum–Saunders Distribution Based on Type-II Censored Data with Application to the Fatigue Life of Aluminum Coupon Cuts

open access: yesMathematics
This study addresses the problem of parameter estimation and prediction for type-II censored data from the two-parameter Birnbaum–Saunders (BS) distribution.
Omar M. Bdair
doaj   +1 more source

Magnetic-Map-Matching-Aided Pedestrian Navigation Using Outlier Mitigation Based on Multiple Sensors and Roughness Weighting

open access: yesSensors, 2019
This research proposes an algorithm that improves the position accuracy of indoor pedestrian dead reckoning, by compensating the position error with a magnetic field map-matching technique, using multiple magnetic sensors and an outlier mitigation ...
Yong Hun Kim   +3 more
doaj   +1 more source

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