Results 41 to 50 of about 2,663,721 (268)
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
wiley +1 more source
Approximate Methods for Maximum Likelihood Estimation of Multivariate Nonlinear Mixed-Effects Models
Multivariate nonlinear mixed-effects models (MNLMM) have received increasing use due to their flexibility for analyzing multi-outcome longitudinal data following possibly nonlinear profiles.
Wan-Lun Wang
doaj +1 more source
The significance of probabilistic risk assessments (PRAs) of nuclear power plants against external events was re-recognized after the Fukushima Daiichi Nuclear Power Plant accident.
Kotaro KUBO +5 more
doaj +1 more source
Stochastic Optimization with Importance Sampling [PDF]
Uniform sampling of training data has been commonly used in traditional stochastic optimization algorithms such as Proximal Stochastic Gradient Descent (prox-SGD) and Proximal Stochastic Dual Coordinate Ascent (prox-SDCA).
Zhang, Tong, Zhao, Peilin
core
There arise two problems when the expectation of some function with respect to a nonuniform multivariate distribution has to be computed by (quasi-) Monte Carlo integration: the integrand can have singularities when the domain of the distribution is unbounded and it can be very expensive or even impossible to sample points from a general multivariate ...
Hörmann, Wolfgang, Leydold, Josef
openaire +3 more sources
Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis +9 more
wiley +1 more source
Selection of proposal distributions for generalized importance sampling estimators [PDF]
The standard importance sampling (IS) estimator, generally does not work well in examples involving simultaneous inference on several targets as the importance weights can take arbitrarily large values making the estimator highly unstable.
Evangelou, Evangelos, Roy, Vivekananda
core +2 more sources
Neural Importance Sampling [PDF]
We propose to use deep neural networks for generating samples in Monte Carlo integration. Our work is based on non-linear independent components estimation (NICE), which we extend in numerous ways to improve performance and enable its application to integration problems.
Thomas Müller +4 more
openaire +2 more sources
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small +3 more
wiley +1 more source
Fully Bayesian Experimental Design for Pharmacokinetic Studies
Utility functions in Bayesian experimental design are usually based on the posterior distribution. When the posterior is found by simulation, it must be sampled from for each future dataset drawn from the prior predictive distribution.
Elizabeth G. Ryan +2 more
doaj +1 more source

