This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li +12 more
wiley +1 more source
US Antibiotic Importation and Supply Chain Vulnerabilities.
Socal MP +5 more
europepmc +1 more source
Importing pancreata for transplantation: a single-center experience across evolving allocation eras. [PDF]
Tamburrini R +10 more
europepmc +1 more source
Proposal for a Council Directive determining the scope of Article 4(1)(d) of Directive 77/388/EEC as regards exemption from value added tax on the final importation of certain goods. SEC (90) 2249 final, 29 November 1990 [PDF]
core
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang +16 more
wiley +1 more source
Regular Plasmodium falciparum importation onto Bioko Island, Equatorial Guinea, hampers malaria elimination from the island. [PDF]
Stabler TC +10 more
europepmc +1 more source
Constitutional Crossroads: Reconciling the Twenty-First Amendment and the Commerce Clause to Evaluate State Regulation of Interstate Commerce in Alcoholic Beverages [PDF]
Douglass, Duncan Baird
core +1 more source
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera +10 more
wiley +1 more source
Modelling the potential use of pre-exposure prophylaxis to reduce nosocomial SARS-CoV-2 transmission. [PDF]
Stewart L +4 more
europepmc +1 more source

