Results 201 to 210 of about 31,688 (268)

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Health inequities in pediatric anaphylaxis: A policy framework and call to action for equitable care from SIAIP allergy prevention commission. [PDF]

Pediatr Allergy Immunol
Grella C, Klain A, Licari A, Manti S, Mori F, Galletta F, Senatore AA, Tomei L, Miraglia Del Giudice M, Marseglia GL, Indolfi C, SIAIP Primary and Secondary Prevention of Allergic Diseases Commission.   +11 more
europepmc   +1 more source

Assessing early detection ability through spatial arrangements in environmental surveillance for poliovirus: A simulation-based study. [PDF]

PLoS One
Asakura TR, O'Reilly KM.
europepmc   +1 more source

Transmission potential of Andes virus from human to human. [PDF]

New Microbes New Infect
Nishiura H, Amemiya Y.
europepmc   +1 more source

When Few Mosquitoes Are Enough: Dengue outbreaks in non-endemic areas. [PDF]

One Health
Pisaneschi G, Manfredi P, Landi A, Stollenwerk N, Aguiar M.   +4 more
europepmc   +1 more source

The issues and challenges of addressing the importation of unregistered pharmaceutical products in Malaysia. [PDF]

J Pharm Policy Pract
Lim LP, Bin Abdul Aziz MF.
europepmc   +1 more source

FelineVMA 2025 hybrid cats position statement. [PDF]

J Feline Med Surg
europepmc   +1 more source

Reconstructing the early spatial spread of pandemic respiratory viruses in the United States. [PDF]

Proc Natl Acad Sci U S A
Zhang R, Deng R, Liu S, Yao Q, Shaman J, Grenfell BT, Viboud C, Pei S.   +7 more
europepmc   +1 more source

Ring vaccination campaign reduces the incidence of dog rabies in N’Djaména, Chad

Perriens L, Zakaria FA, Léchenne M, Alhilou MFA, Zinsstag J, Chitnis N.   +5 more
europepmc   +1 more source