Results 61 to 70 of about 16,983,163 (288)

Epidemiological characteristics and temporal-spatial analysis of overseas imported dengue fever cases in outbreak provinces of China, 2005–2019

Infectious Diseases of Poverty, 2022
Background Overseas imported dengue fever is an important factor in local outbreaks of this disease in the mainland of China. To better prevent and control such local outbreaks, the epidemiological characteristics and temporal-spatial distribution of ...
Xinchang Lun, Yiguan Wang, Chunchun Zhao, Haixia Wu, Caiying Zhu, Delong Ma, Mingfang Xu, Jun Wang, Qiyong Liu, Lei Xu, F. Meng   +10 more
semanticscholar   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

COVID-19 imported cases and severity: expected information from genomic characterization of SARS-CoV-2 strains in Mozambique

Journal of Infection in Developing Countries, 2021
Introduction: The novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), etiological agent of coronavirus disease 2019 (COVID-19) was first reported in China in December 2019 and spread worldwide.
José Sumbana, Alfeu Passanduca, Salvatore Rubino   +2 more
doaj   +1 more source

Family cluster of three cases of monkeypox imported from Nigeria to the United Kingdom, May 2021

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2021
Most reported cases of human monkeypox occur in Central and West Africa, where the causing virus is endemic. We describe the identification and public health response to an imported case of West African monkeypox from Nigeria to the United Kingdom (UK ...
G. Hobson, J. Adamson, H. Adler, R. Firth, S. Gould, C. Houlihan, Christopher Johnson, D. Porter, Tommy Rampling, L. Ratcliffe, K. Russell, A. Shankar, T. Wingfield   +12 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Epidemiological Characteristics and Core Containment Measures of Imported COVID-19 Cases from Abroad in Early Phase in Guangdong, China

Risk Management and Healthcare Policy, 2021
Haiqian Chen,1 Leiyu Shi,2 Yuyao Zhang,1 Xiaohan Wang,1 Gang Sun1 1Department of Health Management, School of Health Management, Southern Medical University, Guangzhou, Guangdong, 510515, People’s Republic of China; 2Department of Health Policy and ...
Chen H, Shi L, Zhang Y, Wang X, Sun G
doaj  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom

Antimicrobial Agents and Chemotherapy, 2017
We present case histories of four patients treated with artemether-lumefantrine for falciparum malaria in UK hospitals in 2015 to 2016. Each subsequently presented with recurrent symptoms and Plasmodium falciparum parasitemia within 6 weeks of treatment ...
C. Sutherland, Paul Lansdell, M. Sanders, Julian K Muwanguzi, Donelly A. van Schalkwyk, H. Kaur, D. Nolder, Julie Tucker, H. Bennett, T. Otto, M. Berriman, Trupti A. Patel, R. Lynn, E. Gkrania-Klotsas, P. Chiodini   +14 more
semanticscholar   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Imported cases of malaria in Spain: observational study using nationally reported statistics and surveillance data, 2002–2015

Malaria Journal, 2019
Malaria was eliminated in Spain in 1964. Since then, more than 10,000 cases of malaria have been reported, mostly in travellers and migrants, making it the most frequently imported disease into this country.
Zaida Herrador, B. Fernández-Martínez, Víctor Quesada-Cubo, Oliva Díaz-García, R. Cano, A. Benito, Diana Gómez-Barroso   +6 more
semanticscholar   +1 more source