Results 71 to 80 of about 4,591,150 (298)

Imported malaria cases in Portugal, from 2010 to 2013 [55].

, 2016
Imported malaria cases in Portugal, from 2010 to 2013 [55].
Carla Sousa (242321), Eduardo Gomes (3332583), Jorge Rocha (115821), César Capinha (2592223)   +3 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Epidemiological and entomological analysis of imported malaria in Pemba Island, Zanzibar: a study from 2020–2022

Malaria Journal
Background Since 2008, Zanzibar has significantly reduced the prevalence of malaria, keeping it at 1%. However, imported malaria particularly from mainland Tanzania continues to pose a major threat to sustaining these gains, especially on Pemba Island ...
Ali O. Ali, Ali M. Ali, Mwema Felix Mwema, Yeromin P. Mlacha   +3 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Demographic characteristics of imported cases of acute infectious diseases in Guangzhou, China, 2005–2019.

, 2022
Demographic characteristics of imported cases of acute infectious diseases in Guangzhou, China, 2005–2019.
Chun-Quan Ou (45848), Chen Shi (415895), Ying Lu (66401), Wen-Hui Liu (4976705), Lei Luo (284798)   +4 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Analysis of imported Chikungunya cases in China from 2006 to 2026

Frontiers in Microbiology
BackgroundChikungunya fever (CHIKF) has impacted 119 countries and regions globally. In 2025, a local outbreak occurred in Guangdong, China, driven by imported cases from Sri Lanka, resulting in over 25,000 diagnoses.
Jiayi Wang, Jiayi Wang, Wenxin Sun, Wenxin Sun, Junxiang Zhao, Junxiang Zhao, Leiliang Zhang, Leiliang Zhang   +7 more
doaj   +1 more source

The number of imported cases of infectious diseases in Guangzhou, 2005–2019.

, 2022
The number of imported cases of infectious diseases in Guangzhou, 2005–2019.
Chun-Quan Ou (45848), Chen Shi (415895), Ying Lu (66401), Wen-Hui Liu (4976705), Lei Luo (284798)   +4 more
core   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source