Results 151 to 160 of about 106,304 (243)

Machine Learning‐Guided Engineering of Protein Phase Separation Properties in Immune Regulation

open access: yesAdvanced Science, EarlyView.
PScalpel, a machine learning model integrating protein structure extraction, graph contrastive learning, and a genetic algorithm, guides the engineering of protein phase separation ability. It adopts transfer learning methods to provide predictive recommendations for protein phase separation ability changes through single amino acid mutations in a ...
Chenqiu Zhang   +9 more
wiley   +1 more source

Emerging Device Applications From Strong Light–Matter Interactions in 2D Materials

open access: yesAdvanced Science, EarlyView.
Two‐dimensional semiconductors enable extremely compact optoelectronic devices such as solar cells, sensors, LEDs, and lasers. Their strong light–matter interactions allow efficient light emission, detection, and energy conversion. This review article discusses the recent progress in integrating these materials with optical cavities and nanostructures ...
Janani Archana K   +7 more
wiley   +1 more source

Multi‐Targeting Non‐Specific Genome Engineering in Bacteria

open access: yesAdvanced Science, EarlyView.
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun   +7 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Asymmetric Mass Transport in Polybromide Ionic Liquids and Its Impact on Dual‐Plating Zinc Bromine Batteries

open access: yesAdvanced Science, EarlyView.
This study elucidates mass transport dynamics within polybromide ionic liquids in dual‐plating zinc–bromine batteries using operando impedance spectroscopy. The findings reveal that sluggish polybromide transport during dissolution contrasts with rapid bromide transport during charging.
Sung Il Kim   +5 more
wiley   +1 more source

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