Results 121 to 130 of about 647,454 (307)

Use of Irreversible Hydrocolloid to Blockout Interproximal Spaces for an Easy Impression Taking

Frontiers in Dentistry, 2009
Making impression to obtain an accurate working cast needs to use accurate impression materials such as polyether. On the other hand, polyether cannot be used easily in places with undercut such as excessive interproximal spaces and under the pontics of ...
A. Monzavi , G. Asadi   +1 more
doaj  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Detail reproduction of elastomeric materials: effect of viscosity and groove geometry / Nik Zarina Nik Mahmood … [et al.] [PDF]

, 2015
Objective: To evaluate the effect of type of viscosity and groove on surface detail reproduction of elastomeric impression materials. Methods: Two polyvinylsiloxane and polyether elastomeric impression materials were investigated.
Nik Mahmood, Nik Zarina
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

In Vitro Effect of Vent Size and Spacer Thickness on Pressure Produced during Maxillary Edentulous Impression Making by Different Impression Materials

Journal of Islamic Dental Association of Iran, 2016
Background and Aim: Inappropriate transfer of pressure during final impression making in fabrication of complete denture can result in ridge resorption.
Tahereh Imani Fouladi, Abbas Fallah Tafti, Mohammad Hoseain Lotfi Kamran, Reza Mostafapour, Majid Sadegh Pourshahab, Maryam Tajaddini   +5 more
doaj  

Evaluation and Comparison of the Dimensional Accuracy of Resultant Casts Made by Monophase Polyether and Monophase Addition Silicone Impression Materials − An In Vitro Study

Journal of Orofacial Sciences
Introduction: Dimensional accuracy when making impressions is crucial to the quality of fixed prosthodontics treatment, and impression materials are critical factors affecting this accuracy.
Raveena Makker, Vivek Choukse, Shilpi G Gupta, Rajeev Srivastava, Sourabh Khandelwal, Prashanthi Reddy   +5 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Penetration and Tensile Strength of Various Impression Materials of Vinylsiloxanether, Polyether, and Polyvinylsiloxane Impression Materials. [PDF]

Eur J Dent, 2022
Apinsathanon P, Bhattarai BP, Suphangul S, Wongsirichat N, Aimjirakul N.   +4 more
europepmc   +1 more source