Results 121 to 130 of about 651,274 (350)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Facade Identification of colonial buildings in the city of Bandung [PDF]
, 2019 Colonial architecture was present in Indonesia through the work of Dutch architects and was intended for the Dutch who lived in Indonesia around the beginning of the 17th century until 1942. At first, Europeans came to Indonesia to trade, then they built
Anwar, H. (Hendi ) +1 more
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
مجله دانشکده دندانپزشکی اصفهان, 2012 Introduction: Complete adhesion of the impression materials to trays is important to prevent impression materials from being pulled away from trays during removed from the mouth and to ensure that the direction of polymerization shrinkage will be towards
Ramin Mosharraf, Zeynab Zareie
doaj
Recommendations for Responsible Food Marketing to Children [PDF]
, 2015 The marketing of unhealthy foods to children and youth is a major public health concern. Children in the United States grow up surrounded by food and beverage marketing, which primarily promotes products with excessive amounts of added sugar, salt, and ...
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Effect of mixing method and storage time on dimensional stability of alginate impressions materials
, 2020 Hyun-Ji Bang +3 more
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Use of Irreversible Hydrocolloid to Blockout Interproximal Spaces for an Easy Impression Taking
Frontiers in Dentistry, 2009 Making impression to obtain an accurate working cast needs to use accurate impression materials such as polyether. On the other hand, polyether cannot be used easily in places with undercut such as excessive interproximal spaces and under the pontics of ...
A. Monzavi +1 more
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