Results 131 to 140 of about 647,454 (307)

Improving the mechanical recycling and reuse of mixed plastics and polymer composites [PDF]

open access: yes, 2009
This is a post-print version of the chapter.In this chapter we will explore the possibilities and viability of commercially recycling and reusing of composites and mixed polymer based waste that is difficult and expensive to separate into individual ...
Tarverdi, K
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effect of a cordless retraction paste on titanium surface: a topographic, chemical and biocompatibility evaluation

open access: yesBrazilian Oral Research, 2013
Good exposure of the preparation margins and haemostasis in the sulcular gingiva are necessary for accurate impressions to produce precise restorations. The use of cordless retraction paste material in implant dentistry is a relatively novel application.
Katherine Cooper   +5 more
doaj  

Facade Identification of colonial buildings in the city of Bandung [PDF]

open access: yes, 2019
Colonial architecture was present in Indonesia through the work of Dutch architects and was intended for the Dutch who lived in Indonesia around the beginning of the 17th century until 1942. At first, Europeans came to Indonesia to trade, then they built
Anwar, H. (Hendi )   +1 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Comparative Evaluation of Dimensional and Occlusal Accuracy of Non-Working Antagonist Casts: A Study on Different Impression Materials and 3D Printing. [PDF]

open access: yesMed Sci Monit, 2023
Al-Makramani BMA   +13 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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