Results 141 to 150 of about 18,499 (269)
Animal Models and Experimental Medicine, EarlyView.The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi +6 more
wiley +1 more source
H19 and IGF2 imprinting from embryogenesis to oncogenesis
Frontiers in Cell and Developmental BiologyThe imprinted H19/IGF2 locus is critical for fetal development and, when dysregulated, contributes to tumorigenesis. This review examines the mechanisms regulating imprinting through DNA methyltransferases, alongside shared signaling pathways, such as ...
Bella Ortega +4 more
doaj +1 more source
European Medical Journal, 2019 Since the birth of the first in vitro fertilisation baby in 1978, >5 million babies have been born worldwide using assisted reproductive technologies (ART).
Delia Hutanu +2 more
doaj
Imprinting disorders in Estonia
, 2019 Congenital imprinting disorders (ImpDis) are a little-known group of rare hereditary diseases caused by changes in the expression of imprinted genes, mainly affecting growth, brain functions and the hormonal system. Although at least 100 imprinted genes have been found in the human genome, only 13 clinically recognizable ImpDis are currently known. The
openaire +1 more source
Long‐Range Interactions in Topological Superconducting Systems: A Mini Review
Advanced Physics Research, EarlyView.Long‐range interacting quantum systems are surveyed in this review, with an emphasis on the long‐range topological superconductor and its variants. Long‐range interactions decaying in a power‐law manner can lead to exotic phenomena that finds no analogue in short‐range regimes.
Juntong Ren, Haifeng Lü
wiley +1 more source
Molecular studies of genomic imprinting using an Angelman syndrome imprinting defect mouse model
, 2008 Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are distinct neurobehavioral disorders associated with the loss of paternally or maternally expressed imprinting genes within human chromosome 15q11-q13, respectively.
Hou, Aihua
core +1 more source
Guiding and Manipulating Light Fields in Microstructured Liquid Crystals
Advanced Physics Research, EarlyView.This review summarizes recent advances in guided‐wave optics enabled by microstructured liquid crystal (LC) devices, covering their fundamental material properties, key degree of freedom for dynamic light field manipulations. The advances of linear guided‐wave optics, nonlinear‐optics with spatial optical solitons, and microlasers in LC‐based devices ...
Shan‐shan Chang +2 more
wiley +1 more source
Epigenetic discordance at imprinting control regions in twins
, 2011 Imprinting control regions are differentially methylated in a parent-of-origin-dependent manner and this methylation state is inherited through the germline. These regions control parent-specific monoallelic expression of their target genes. Genetically
Jeffrey M Craig, Miina Ollikainen
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla +13 more
wiley +1 more source