Immunocontraception of male and female giraffes using the GnRH vaccine Improvac®. [PDF]
I Protocols for contraception using the GnRH vaccine Improvac® were developed. A clear reduction of fecal hormone metabolites in female giraffes was achieved with three, and in males with four or five injections at 4‐week intervals. Effective booster injections were administered at 2‐month intervals in the first, and at three to 4‐month intervals in ...
Schwarzenberger F +13 more
europepmc +3 more sources
Effects of an anti-gonadoliberin releasing hormone vaccine on testicular, epididymal and spermatogenic development in the horse. [PDF]
Abstract The effects of the GnRH vaccine Improvac® on testicular and epididymal morphometrics, histology and spermatogenesis were measured in 19 young (15–20 months) colts randomly assigned to one control (saline, castration at 57 days, n = 6) or either of two GnRH vaccine‐treatment groups, T‐57 (castration at 57 days, n = 7) or T‐100 (castration at ...
Botha AE +7 more
europepmc +2 more sources
Advances in the ultrasound diagnosis in equine reproductive medicine: New approaches. [PDF]
Abstract Ultrasound technology has led to new lines of research in equine reproduction, and it has helped to greatly improve clinical diagnosis and reproductive outcomes in equine practice. This review aims to discuss the potential clinical uses and new approaches of ultrasonography in equine reproduction.
Ortega-Ferrusola C +6 more
europepmc +2 more sources
Immunocastration in adult boars as a model for late-onset hypogonadism. [PDF]
Abstract Background While immunocastration has been studied in male pre‐pubertal pigs, data on older, sexually mature animals are limited. To understand the physiological effects of androgen deprivation in the late sexual development phase, we compared mature immunocastrated boars (n = 19; average age = 480 days) to young male immunocastrated pigs (n =
Batorek-Lukač N +8 more
europepmc +2 more sources
Early vaccination with Improvac®: effects on performance and behaviour of male pigs
The aim of this study was to investigate the effect of giving a two-dose regimen of gonadotropin-releasing hormone vaccine, Improvac® (Pfizer Ltd), earlier than currently recommended, on performance and behaviour of growing/finishing pigs.
K. Andersson +3 more
doaj +2 more sources
GnRH-Based Immunocastration Vaccines: Comparative Analysis and Role in Boar Taint Reduction [PDF]
Boar taint is a persistent challenge in pork production, caused primarily by the accumulation of androstenone and skatole in adipose tissue. It affects 5–40% of uncastrated male pigs and is perceived negatively by a substantial proportion of consumers ...
Jisang Kim +2 more
doaj +2 more sources
Effects of GnRH vaccination in wild and captive African Elephant bulls (Loxodonta africana) on reproductive organs and semen quality. [PDF]
Although the African elephant (Loxodonta africana) is classified as endangered by the International Union for Conservation of Nature (IUCN), in some isolated habitats in southern Africa, contraception is of major interest due to local overpopulation ...
Imke Lueders +9 more
doaj +2 more sources
Abstract In cervids, blood biochemical markers may reflect changes in various physiological and environmental factors, especially in response to changes in metabolism following nutrient supplementation or the manipulation of hormone production. Decreasing androgen production through immunocastration (IC) to ease the husbandry of male animals is ...
Veit Ny +6 more
wiley +1 more source
[Oestrus suppression in a dairy herd by means of anti-GnRH vaccination Improvac®: A prospective field study]. [PDF]
INTRODUCTION The aim of this study was to evaluate the duration of estrus suppression after a double administration of the anti-GnRH vaccine Improvac® (Zoetis Schweiz GmbH, 2800 Delémont) in cows.
Hirsbrunner, Gabriela +2 more
core +2 more sources
Suppression of reproductive behaviour and gonadal function in female horses—An update
Abstract The behaviour of mares is often detrimental to their performance resulting in frequent demand for methods to suppress gonadal function. In addition, prevention of unintended reproduction especially in feral horse populations may require methods for suppression of gonadal function.
Christine Aurich, Martim Kaps
wiley +1 more source

