Results 61 to 70 of about 7,725,753 (253)
Journal of Pharmaceutical Policy and Practice, 2017 Background Medicines use related challenges such as inadequate adherence, high levels of antimicrobial resistance and preventable adverse drug reactions have underscored the need to incorporate pharmaceutical services to help achieve desired treatment ...
Niranjan Konduri +3 more
doaj +1 more source
Microbial Cell Factories, 2018 Background The bacterium E. coli is a major host for recombinant protein production of non-glycosylated products. Depending on the expression strategy, the recombinant protein can be located intracellularly.
Christoph Slouka +7 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Integrating food safety and nutrition for improved health and wellbeing: A new lens on food system frameworks [PDF]
, 2021 Global Alliance for Improved Nutrition
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Peaked-Density Profile Mode and Improved Confinement in Helical Systems [PDF]
, 1990 The difference in the effect of the peaked density profile on the improved transport between tokamaks and toroidal-helical systems is discussed. Based on the theory that the rotational shear causes the inward pinch in tokamaks, the magnitude of the ...
Itoh, S.-I., Itoh, K.
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PlantsDegradation of shoots, characterized by stunted growth and signs of water deficit, is common in bamboo stands. However, the specific mechanisms underlying water utilization in degrading shoots remain unclear.
Tianyi Hu +6 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2022 This is a Thematic paper within the report Paudel, N.S., Ojha, H., Banjade, M.R., Karki, R. and Tamang, S. (Eds.). 2021. Revitalising community forestry in the changing socioeconomic context of Nepal.
Nuberg, I., Cedamon, E., Bardsley, D.
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