Results 111 to 120 of about 2,458,834 (308)

Measuring the processes and outcomes of value management studies in construction

open access: yes, 2005
7th International Value Conference 2005: Why Re-Invent the Wheel?, Hong Kong, 2-3 June 2005Value management (VM) is a useful tool in coping with many challenges faced by the construction industry today.
Shen, Q   +7 more
core  

Application of particle swarm optimization in dynamic optimization of constrained stand-off layer damping structure

open access: yesZhongguo Jianchuan Yanjiu, 2018
[Objectives] In order to further improve the vibration characteristics of traditional constrained damping structures, the optimized design of an improved constrained stand-off layer damping structure with engineering application value is carried out ...
YI Shaoqiang, HE Shiping, WANG Jie
doaj  

From Triportal to Uniportal Video-Thoracoscopic Lobectomy: The Single Surgeon Learning Curve by CUSUM Chart and Perioperative Outcomes

open access: yesSurgical Techniques Development
Background: Uniportal video-thoracoscopic lobectomy has improved postoperative outcomes in lung cancer patients. Thus, thoracic surgeons are increasingly required to learn this new approach.
Giorgia Cerretani   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Farmers’ preferential choice decisions to alternative cassava value chain strands in Morogoro rural district, Tanzania

open access: yes
The study was conducted to determine farmers’ preferential choice decision of alternative cassava value chain strands and as well as factors behind such decisions in Morogoro rural District, Tanzania. Factor analysis was first used to reduce and identify
Mdoe, N. Y. S.   +2 more
core  

The Value of Health and Longevity [PDF]

open access: yes
We develop an economic framework for valuing improvements to health and life expectancy, based on individuals' willingness to pay. We then apply the framework to past and prospective reductions in mortality risks, both overall and for specific life ...
Robert H. Topel, Kevin M. Murphy
core  

The value of a value: The benefits of improved decision making informed by non-market valuation

open access: yes
Information on non-market values has the potential to improve decision making but approaches to measure these values are costly and may be inaccurate. This study develops a Bayesian value of information (VOI) model to evaluate when and if the benefit of ...
Pannell, David J.   +9 more
core   +1 more source

Improved Synthesis of Icosahedral Carboranes Containing Exohedral B–c and C–c Bonds

open access: yes, 2018
We report improved methods utilizing orthogonal chemistry to achieve efficient substitution at electron-rich B-vertices and electron-poor C-vertices of carborane.
Alexander, Spokoyny   +6 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Executive Stock Option Exercises and the Predictive Ability of Transaction Value

open access: yes, 2004
This paper investigates the predictive ability of executives’ stock option exercises by categorising all exercises by the overall value of the transaction. This measure incorporates the cost to the executive of exercising the option, together with the
Mase, B, Kyriacou, K
core  

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