Results 81 to 90 of about 3,421,975 (283)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Sensitivity of an improved method for post-life laboratory diagnosis of chicken eimeriosis
Ukrainian Journal of Veterinary and Agricultural SciencesPoultry farming is vital in providing the population with high-quality food products – eggs and poultry meat. Poultry farming is characterized by rapid livestock reproduction rates, the lowest per unit of output compared to other livestock industries. To
V. Hodyna
doaj +1 more source
Can improved agricultural water use efficiency save India’s groundwater?
Environmental Research Letters, 2015 Irrigated agriculture is placing increasing pressure on finite freshwater resources, especially in developing countries, where water extraction is often unregulated, un-priced and even subsidized.
Ram Fishman +2 more
doaj +1 more source
The major thrusts proposed for GaAs were increased efficiency and improved radiation damage data. Current laboratory production cells consistently achieve 16 percent AMO one-Sun efficiency.
Conway, E. J.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Cancer Management and Research, 2020 Fu Xiong,1,2,* Yanyan Cao,1,2,* Xiaopeng Guo,1,2 Hongsen Zhang,1,2 Jihua Wang,1,2 Bin Xiong,1,2 Bin Liang,1,2 Chuansheng Zheng1,2 1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan ...
Xiong F +7 more
doaj
Achromatic Fresnel Lens with Improved Efficiency for PV Systems
International Journal of Photoenergy, 2014 This work is aimed to design and evaluate different achromatic Fresnel lens solutions capable of operating as concentrators aimed at photovoltaic cells systems. Throughout this study, the theoretical parametric design of the achromatic lens will be shown
Mario González Montes +4 more
doaj +1 more source
Study of a model for the folding of a small protein
, 2005 We describe the results obtained from an improved model for protein folding. We find that a good agreement with the native structure of a 46 residue long, five-letter protein segment is obtained by carefully tuning the parameters of the self-avoiding ...
Andrea Nobile +4 more
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source