Results 121 to 130 of about 9,646,676 (303)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Вестник университета, 2019 In this article features of influence of an ecological factor of development of urban areas on formation of improvement of the cities, the most expedient ways of providing a favorable ecological situation of urban areas, major factors interfering ...
A. Z. Al-Fahad
doaj
CIMMYT - Proposed Five Year Plan, 1971-1975 [PDF]
, 1970 Document discussed by CIMMYT Board in September 1970. Includes a brief history of CIMMYT and identification of new factors influencing the center's expanding operations and changes to its existing programs, including increased emphasis on the problems of
International Maize and Wheat Improvement Center
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Farmers Groups In Selected States Of Nigeria: A Need For Capacity Improvement
Journal of Agricultural Extension, 2017 This study evaluated the characteristics ofFGs in Gombe, Kaduna andNiger states of Nigeria. Primary data for the study was collected through reconnaissance observation, group discussionsandstructuredinterviews with the FGmembers while secondary data were
Y M Abdullahi, S J Auta, J G Akpoko
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Acta Scientiarum: Animal Sciences, 2008 Este trabalho avaliou as características: idade, peso, ganho de peso diário (GPD), ingestão de matéria seca (IMS), conversão alimentar (CA), eficiência alimentar (EA) e consumo alimentar residual (CAR) de tourinhos da raça Nelore Mocho em prova de ...
Marcio de Nadai Bonin +5 more
doaj
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source