Results 131 to 140 of about 5,830,633 (260)

Role of IDRC in Eastern Africa National Sorghum Improvement Programs

open access: yes, 1983
Meeting: Regional Workshop on Sorghum Improvement in Eastern Africa, 17-21 Oct. 1982, Nazreth, ETMeeting: Regional Workshop on Sorghum Improvement in Eastern Africa, 17-21 Oct.
Kirkby, R.A.
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

DRAFT Oregon health improvement plan : 2011-2020

open access: yes, 2010
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF cover (viewed on October 15, 2015)."October ...

core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Quality and Patient Safety Division Annual Report 2014

open access: yes, 2015
A work plan is developed on an annual basis to support the quality and patient safety objectives in the National Service Plan. This report reviews the work completed in 2014 in delivery of the 2013 plan.
Quality Improvement Division
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Sorghum improvement in Eastern Africa : proceedings of the Regional Workshop on Sorghum Improvement in Eastern Africa, 17-21 Oct., 1982, Nazreth and Debre Zeit, Ethiopia

open access: yes, 1983
Meeting: Regional Workshop on Sorghum Improvement in Eastern Africa, 17-21 Oct. 1982, Nazreth, ETMeeting: Regional Workshop on Sorghum Improvement in Eastern Africa, 17-21 Oct.

core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Minutes of the Trustees of the Internal Improvement Fund, State of Florida.

open access: yes, 1919
Includes also Financial statement.Includes also Financial statement.Mode of access: Internet.Published under authority of Trustees by ... Secretary.Continues: Florida. Trustees of Internal Improvement Fund.
Florida. Trustees of Internal Improvement Fund.
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