Results 51 to 60 of about 5,592,241 (297)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
IEEE Access, 2018 The impulse system radar is based on the generation, transmission, radiation, receiving, data collection, data processing, and imaging of impulse signals.
Longfei Dang, Hongchun Yang, Baohua Teng
doaj +1 more source
Which impulse response function? [PDF]
, 2011 This paper compares standard and local projection techniques in the production of impulse response functions both theoretically and empirically. Through careful selection of a structural decomposition, the comparison continues to an application of US ...
Ronayne, David
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
PENGARUH SHOPPING LIFESTYLE DAN HEDONIC CONSUMPTION TERHADAP IMPULSE BUYING PADA TOKOPEDIA [PDF]
, 2022 Penelitian ini bertujuan untuk mengetahui pengaruh Shopping Lifestyle, Hedonic Consumption terhadap Impulse Buying. Penelitian ini dilakukan pada e-commerce Tokopedia.
Purwanto, Sugeng, Qammaidha, Lailla Nur
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Lightning Impulse Ageing of HV Cable Insulation
, 2009 Lightning impulses can lead to accelerated ageing of extruded cables. Electrical behaviour of a dielectric material when experiencing a lightning impulse is different to that for DC or power frequency applied voltages.
Dao, N L, Swingler, S G, Lewin, P L
core +1 more source
Net Impulse and Net Impulse Characteristics in Vertical Jumping [PDF]
, 2012 The purpose of this dissertation was to explore the potential use of net impulse and its characteristics in vertical jumping to monitor athletes\u27 performance status and responses/adaptations to interventions.
Mizuguchi, Satoshi
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source