Results 71 to 80 of about 421,331 (286)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
AerospaceThe ablation impulse of typical asteroid simulants irradiated by a nanosecond pulsed laser has been investigated in a vacuum environment. A torsional pendulum measurement system was constructed to calculate the impulse of laser ablation.
Yingjie Ma +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Feature Extraction of Weak Fault for Rolling Bearing based on Spectral Kurtosis and MOMEDA
Jixie chuandong, 2021 Aiming at the problem that the early periodic transient impulse of rolling bearings is not obvious and the spectral kurtosis is poorly analyzed under low signal-to-noise ratio， a method of extracting the weak fault features of rolling bearing based on ...
Fuwang Liang, Huer Sun, Kexin Liu
doaj
A method of describing the spontaneous activity of nerve units that exhibit a stochastic dead time [PDF]
Statistical characteristics of spontaneous electrical activity of nerve units that exhibit stochastic dead time following ...
Aoyagi, M.
core +1 more source
Video enhancement using adaptive spatio-temporal connective filter and piecewise mapping [PDF]
, 2008 This paper presents a novel video enhancement system based on an adaptive spatio-temporal connective (ASTC) noise filter and an adaptive piecewise mapping function (APMF).
A Polesel +31 more
core +4 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Upper stages utilizing electric propulsion [PDF]
The payload characteristics of geocentric missions which utilize electron bombardment ion thruster systems are discussed. A baseline LEO to GEO orbit transfer mission was selected to describe the payload capabilities.
Byers, D. C.
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source