Results 61 to 70 of about 6,001,787 (300)

Research on the dynamic characteristics of the cavitation bubble collapsing between multiple particles

open access: yesUltrasonics Sonochemistry
The combined action of multiple particles and cavitation bubbles can severely damage hydraulic machinery. Combining the Kelvin impulse theory and the results of high-speed photography experiments, this paper researches the dynamic behaviors of a single ...
Xiaoyu Wang   +4 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Effects of Electrical Stimulation with Different Impulses on Physical Characteristics of Rabbit Meat

open access: yesAnimal Production: Indonesian Journal of Animal Production, 2010
Meat becoming less tender with age. One of the methods to increase the meat tenderness is by electrical simulation. The objective of this study was to investigate the effect of electrical simulation with different level of impulses on physical ...
H Yurmiati, GA Wiedy, S Kusmajadi
doaj  

Study on Spatial-Temporal Distribution Characteristics of the Discharge Process in a 1 m Rod-Plate Gap Under Different Polarity Lightning Impulses

open access: yesIEEE Access, 2019
The observation of the air gap discharge process is the basis of revealing the physical mechanism of gas discharge and establishing the accurate numerical simulation model.
Yaqi Zhang   +7 more
doaj   +1 more source

Tower impulse grounding resistance measurement based on multiple frequency impedance

open access: yesIET Generation, Transmission & Distribution, 2023
Tower impulse grounding resistance is important for judging the lightning protection performance of transmission lines. Therefore, it is significant to accurately measure the tower impulse grounding resistance. Existing measurement methods mainly contain
Yihua Dan   +5 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Characteristics analysis of muzzle impulse noise based on wavelet energy spectrum

open access: yesJournal of Measurement Science and Instrumentation, 2015
Because muzzle impulse noise could cause damage to or have an influence on the operator,the effective protective measures should be taken.Therefore,correct analysis of impulse noise characteristics is very significant.Considering the shortcomings of fast
LAI Fu-wen   +3 more
doaj  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Effect of Cross-Linking on the Electrical Properties of LDPE and its Lightning Impulse Ageing Characteristics

open access: yes, 2011
Cross-linked polyethylene (XLPE) is commonly used within high voltage cable insulation. It has improved thermal and mechanical resistance compared to normal low density polyethylene (LDPE).
Dao, N L, Swingler, S G, Lewin, P L
core   +1 more source

Seasonal Influences on the Impulse Characteristics of Grounding Systems for Tropical Countries

open access: yesEnergies, 2019
One of the most important parameters of the performance of grounding systems is the soil resistivity. As generally known, the soil resistivity changes seasonally, hence the performance of grounding systems, at DC and under high impulse conditions.
Muhd Shahirad Reffin   +6 more
doaj   +1 more source

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