Results 61 to 70 of about 581,049 (289)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Impulse Control Disorders are Associated with Multiple Psychiatric Symptoms in Parkinson's Disease

Journal of Parkinson’s Disease, 2014
Background: Impulse control disorders can have serious adverse consequences to the life of a patient with Parkinson's disease. Although impulse control disorders are common, a possible psychiatric comorbidity has not been fully characterized.
Elina Jaakkola, Valtteri Kaasinen, Chiara Siri, Kirsti Martikainen, Roberto Cilia, Solja Niemelä, Juho Joutsa   +6 more
doaj   +1 more source

Barratt Impulsivity in Healthy Adults Is Associated with Higher Gray Matter Concentration in the Parietal Occipital Cortex that Represents Peripheral Visual Field

Frontiers in Human Neuroscience, 2017
Impulsivity is a personality trait of clinical importance. Extant research focuses on fronto-striatal mechanisms of impulsivity and how executive functions are compromised in impulsive individuals.
Jaime S. Ide, Hsiang C. Tung, Cheng-Ta Yang, Yuan-Chi Tseng, Chiang-Shan R. Li, Chiang-Shan R. Li, Chiang-Shan R. Li, Chiang-Shan R. Li   +7 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Event-Triggered Impulsive Formation Control for Cooperative Obstacle Avoidance of UAV Swarms in Tunnel Environments

Drones
UAV formation navigation in complex environments such as narrow tunnels faces multiple challenges, including obstacle avoidance, formation maintenance, and communication constraints.
Rui Hao, Wenjie Zhou, Yuanfan Wang, Yuehao Yan   +3 more
doaj   +1 more source

Dietary Long-Chain Omega-3 Fatty Acids Are Related to Impulse Control and Anterior Cingulate Function in Adolescents

Frontiers in Neuroscience, 2019
Impulse control, an emergent function modulated by the prefrontal cortex (PFC), helps to dampen risky behaviors during adolescence. Influences on PFC maturation during this period may contribute to variations in impulse control.
Valerie L. Darcey, Valerie L. Darcey, Goldie A. McQuaid, Diana H. Fishbein, John W. VanMeter   +4 more
doaj   +1 more source

Expanding the spectrum of impulse control disorders in Parkinson's disease: the phenomenology of sweet craving [PDF]

, 2013
Thesis (M.A.)--Boston UniversityBackground: The recognized spectrum of impulse control disorders in Parkinson’s disease (PD) includes pathologic gambling, hypersexuality, compulsive buying, and binge eating, and is commonly related to exposure to ...
Brown, Caitlin Harrington
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Distinct Response Inhibition Patterns in Obsessive Compulsive Disorder Patients and Pathological Gamblers

Frontiers in Psychiatry, 2018
Background: Obsessive-compulsive disorder (OCD) and pathological gambling (PG) are common disorders. The cognitive models of OCD and PG focus on abnormalities in response inhibition.
Semion G. Kertzman, Semion G. Kertzman, Michael Poyurovski, Michael Poyurovski, Sarit Faragian, Ronit Weizman, Koby Cohen, Anat Aizer, Abraham Weizman, Abraham Weizman, Pinhas N. Dannon, Pinhas N. Dannon   +11 more
doaj   +1 more source

POSITIONAL IMPULSE AND DISCONTINUOUS CONTROLS FOR DIFFERENTIAL INCLUSION

Ural Mathematical Journal, 2020
Nonlinear control systems presented in the form of differential inclusions with impulse or discontinuous positional controls are investigated. The formalization of the impulse-sliding regime is carried out.
Ivan A. Finogenko, Alexander N. Sesekin
doaj   +1 more source