Results 221 to 230 of about 2,085,793 (277)

State monitoring of rolling bearings in vibration-based anchor drilling rig based on machine learning model. [PDF]

Sci Rep
Hou Q, Chen Z, Song Y, Wang X, Yu Z.
europepmc   +1 more source

Essential work, invisible workers: The role of digital curation in COVID‐19 Open Science

Journal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 703-717, April 2025.
Abstract In this paper, we examine the role digital curation practices and practitioners played in facilitating open science (OS) initiatives amid the COVID‐19 pandemic. In Summer 2023, we conducted a content analysis of available information regarding 50 OS initiatives that emerged—or substantially shifted their focus—between 2020 and 2022 to address ...
Irene V. Pasquetto, Amina A. Abdu, Natascha Chtena   +2 more
wiley   +1 more source

A unified theory of restrictive and addictive eating: a life course model integrating generational transmission, neurodevelopmental risk, and ultra-processed food use disorder-a theoretical review. [PDF]

J Eat Disord
Wiss DA, Logan AC.
europepmc   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

The Sentinel Phenotype: a theoretical bioenergetic and neurobiological framework for high-fidelity predictive systems (HEPOE Theory). [PDF]

Front Neurosci
Brezolin CLM, de Freitas SB.
europepmc   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

Minor Resistance: The Everyday Politics and Power Dynamics of Assistive Technology Adoption. [PDF]

ASSETS
Hsueh S, Van Dusen D, Caspi A, Mankoff J.   +3 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

The Psychopathological Domains of Attachment Trauma: A Proposal for a Clinical Conceptualization. [PDF]

Clin Neuropsychiatry
Farina B, Schimmenti A.
europepmc   +1 more source

Triboelectric-electromagnetic hybrid nanogenerator for harvesting blue energy and creating an ocean wave warning system. [PDF]

Nanoscale Adv
Wang W, Zhang Y, Wu G, Zhao Z, Wu Y, Zheng H.   +5 more
europepmc   +1 more source