Results 61 to 70 of about 506,254 (285)

Estimation of Effective Length of Type-A Grounding System According to IEC 62305-3 Using a Machine Learning Regression Model

open access: yesApplied Sciences
Two types of grounding systems are recommended for use in the international standard IEC 62305-3, Part 3: Physical damage to structures and life hazard.
Dino Lovrić   +2 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Active-Support Integrated Control Method for Renewable Energy Generation Voltage Source Converters

open access: yesFrontiers in Energy Research, 2022
Aiming at the grid connection stability of renewable energy generation Voltage Source Converters (VSCs), an active support integrated control strategy is proposed in this article.
Chu Tianfeng   +6 more
doaj   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

The HISSTools Impulse Response Toolbox: Convolution for the Masses [PDF]

open access: yes, 2012
This paper introduces the HISSTools project, and its first release, the HISSTools Impulse Response Toolbox (HIRT); a set of tools for solving problems relating to convolution and impulse responses (IRs).
Harker, Alexander   +3 more
core   +3 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Application of Impulse Response Characteristics in Rail-ground Transition Resistance Measurement

open access: yesChengshi guidao jiaotong yanjiu
Objective The stray current harm in urban rail transit lines is increasingly non-ignorable. Stray current is not easy to be detected, and the amount of the rail-ground transition resistance is a crucial factor affecting stray current.
CAO Xiaobin   +5 more
doaj   +1 more source

Dynamic impedance model of the skin-electrode interface for transcutaneous electrical stimulation. [PDF]

open access: yesPLoS ONE, 2015
Transcutaneous electrical stimulation can depolarize nerve or muscle cells applying impulses through electrodes attached on the skin. For these applications, the electrode-skin impedance is an important factor which influences effectiveness.
José Luis Vargas Luna   +3 more
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang   +13 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

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