Results 51 to 60 of about 7,978 (254)

Application of Impulse Response Characteristics in Rail-ground Transition Resistance Measurement

Chengshi guidao jiaotong yanjiu
Objective The stray current harm in urban rail transit lines is increasingly non-ignorable. Stray current is not easy to be detected, and the amount of the rail-ground transition resistance is a crucial factor affecting stray current.
CAO Xiaobin, YE Jun, WANG Manxiang, JI Yaozheng, JIAN Minghua, XIE Jinyang   +5 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Comparison of Motion Artefact Reduction Methods and the Implementation of Adaptive Motion Artefact Reduction in Wearable Electrocardiogram Monitoring

Sensors, 2020
A motion artefact is a kind of noise that exists widely in wearable electrocardiogram (ECG) monitoring. Reducing motion artefact is challenging in ECG signal preprocessing because the spectrum of motion artefact usually overlaps with the very important ...
Xiang An, George K. Stylios
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Sparse signal recovery based on adaptive algorithms for debris detector

AIP Advances, 2021
Inductive debris sensors are generally used in online debris detection and perform well in monitoring the wear condition of rotating facilities. The detection accuracy is restricted by the superposition and noise of the impedance signal.
Bingsen Xue, Xingming Zhang, Yunzhe Xu, Yehui Li, Hongpeng Zhang, Changli Yu   +5 more
doaj   +1 more source

Impulsive impedances in lossless circuits: Fourierand Laplace methods

Electronics Letters, 2000
A proposal for adding impulsive components of impedance/admittance to the reactance/susceptance for lossless transmission lines is extended to all lossless resonant circuits. This new Fourier analysis yields a finite rate of energy transfer from a lossless source while the orthodox analysis would give an unbounded steady-state energy transfer.
openaire   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Experimental Investigation on Cumulative Effects of Transformer Winding Deformation Under Short‐Circuit Impulses

IET Electric Power Applications
Power transformer windings are susceptible to deformation after multiple short‐circuit impulses, threatening power grid stability. Currently, there is a lack of experimental data on various characteristic parameters of failures after multiple short ...
Jun Liu, She Chen, Feng Wang, Dengfeng Zhu, Xu Li, Yao Zhong, Zhongxiang Li   +6 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source