Results 41 to 50 of about 540,313 (279)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Nonparametric estimation of mark's distribution of an exponential Shot-noise process [PDF]
, 2015 In this paper, we consider a nonlinear inverse problem occurring in nuclear science. Gamma rays randomly hit a semiconductor detector which produces an impulse response of electric current.
Ilhe, Paul +3 more
core +5 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Computing Impulse Response of Room Acoustics Using the Ray-Tracing Method in Time Domain
Archives of Acoustics, 2013 This paper proposes a new approach for calculating the impulse response of room acoustics. Impulse response provides unique characterization of any discrete linear-time invariant (LTI) systems.
Adil ALPKOCAK, Malik Kemal SIS
doaj
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Frontiers in Built EnvironmentA triple impulse is used as a mathematical model of forward-directivity inputs, which are fault-normal components of near-fault earthquake ground motions. In this paper, two types of the triple impulse input are employed.
Kotaro Kojima, Izuru Takewaki
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Algorithm of underdetermined convolutive blind source separation for high reverberation environment
Tongxin xuebao, 2023 To separate the underdetermined convolutive mixture signals in the high reverberation environment, a novel algorithm of underdetermined convolutive blind source separation was proposed.Aiming at the influence of high reverberation environment, a global ...
Yuan XIE +3 more
doaj +2 more sources
Electronic Journal of Structural Engineering, 2015 This paper presents a structural damage identification approach based on the time domain impulse response functions, which are extracted from the measured dynamic responses with the input available.
Jun Li, Hong Hao, XINGYU FAN
doaj +1 more source