Results 61 to 70 of about 1,771,267 (214)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dynamic Calibration and Validation of an Accelerometer Force Balance for Hypersonic Lifting Models

The Scientific World Journal, 2014
An accelerometer-based force balance was designed and developed for the measurement of drag, lift, and rolling moment on a blunt-nosed, flapped delta wing in a short-duration hypersonic shock tunnel. Calibration and validation of the balance were carried
Prakash Singh, Sharad Trivedi, Viren Menezes, Hamid Hosseini   +3 more
doaj   +1 more source

Effect of High-k Oxide on Double Gate Transistor Embedded in RF Colpitts Oscillator [PDF]

Журнал нано- та електронної фізики, 2016
The Linear Time Variant (LTV) model of phase noise is considered. It is based on the Impulse Sensitivity Function (ISF) which describes carefully the sensitivity of an oscillator to a parasite impulse current injection in different nodes of the circuit.
M. Bella, S. Latreche, C. Gontrand
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Spatial Sound Rendering Using Intensity Impulse Response and Cardioid Masking Function

Applied Sciences
This study presents a new technique for creating spatial sounds based on a convolution processor. The main objective of this research was to propose a new method for generating a set of impulse responses that guarantee a realistic spatial experience ...
Witold Mickiewicz, Mirosław Łazoryszczak   +1 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Dynamic focusing of an ultrasonic be am by means of a phased annular array using a pulse technique

Archives of Acoustics, 2016
An approach to compute, the transient radiation resulting from an impulse velocity motion of an array of annular pistons in a rigid planar infinite baffle is presented.
Tamara KUJAWSKA
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Modeling the Relationship between Exchange Rate and other Macroeconomic Variables: Case Study of Iran (BVAR Approach with SSVS Prior) [PDF]

Faslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2013
The exchange rate is an important economic variable which affects other macroeconomic variables through different channels. This article estimates the effects of exchange rate shocks on macroeconomic variables of Iranian economy by applying Bayesian VAR ...
Mahdi Sadeghi Shahdani, Hamed Saheb-Honar, Ali Taheri Fard, Seyyed Reza Nakhli   +3 more
doaj  

On the Volatility Spillover between Agricultural Commodities and Latin American Stock Markets

Risks, 2018
Addressing the volatility spillovers of agricultural commodities is important for at least two reasons. First, for the last several years, the volatility of agricultural commodity prices seems to have increased.
Vincenzo Candila, Salvatore Farace
doaj   +1 more source