Results 101 to 110 of about 688,832 (367)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

ULF waves excited by negative/positive solar wind dynamic pressure impulses at geosynchronous orbit [PDF]

, 2010
X. Y. Zhang, Qiugang Zong, Yongfu Wang, Hui Zhang, Lun Xie, S. Y. Fu, Chongjing Yuan, Chao Yue, B. Yang, Z. Y. Pu   +9 more
openalex   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Existence of solutions for impulsive neutral functional differential equations with multiple delays

Electronic Journal of Differential Equations, 2008
In this paper an existence result for initial value problems for first order impulsive neutral functional differential equations with multiple delay is proved under weak conditions.
Mustapha Lakrib
doaj  

A note on stability of impulsive scalar delay differential equations

Electronic Journal of Qualitative Theory of Differential Equations, 2016
For a class of scalar delay differential equations with impulses and satisfying a Yorke-type condition, criteria for the global asymptotic stability of the zero solution are established.
Teresa Faria, José Oliveira
doaj   +1 more source

On the existence and exponential attractivity of a unique positive almost periodic solution to an impulsive hematopoiesis model with delays

, 2015
In this paper, a generalized model of hematopoiesis with delays and impulses is considered. By employing the contraction mapping principle and a novel type of impulsive delay inequality, we prove the existence of a unique positive almost periodic ...
Anh, Trinh Tuan, Van Hien, Le, Van Nhung, Tran   +2 more
core   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Oscillation of high order linear functional differential equation with impulses

Electronic Journal of Differential Equations, 2005
We study the solutions to high-order linear functional differential equations with impulses. We improve previous results in the oscillation theory for ordinary differential equations and obtain new criteria on the oscillation of solutions.
Haihua Liang, Weizhen Feng
doaj  

The Strict Stability of Impulsive Differential Equations with a Caputo Fractional Derivative with Respect to Other Functions

Fractal and Fractional
The aim of this paper is to study a nonlinear system of impulsive fractional differential equations and Caputo fractional derivatives with respect to another function (CFF).
Ravi P. Agarwal, Snezhana Hristova, Donal O’Regan   +2 more
doaj   +1 more source