Results 71 to 80 of about 675,673 (375)

The Enterprise of Socratic Metaethics [PDF]

, 2000
That human beings have the potential for rationality and the ability to cultivate it is a fact of human nature. But to value rationality and its subsidiary character dispositions - impartiality, intellectual discrimination, foresight, deliberation ...
Piper, Adrian M. S.
core  

impulse

, 2000
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Periodic impulsive fractional differential equations

Advances in Nonlinear Analysis, 2017
This paper deals with the existence of periodic solutions of fractional differential equations with periodic impulses. The first part of the paper is devoted to the uniqueness, existence and asymptotic stability results for periodic solutions of ...
Fečkan Michal, Wang Jin Rong
doaj   +1 more source

Impulse distributions in dense granular flows: signatures of large-scale spatial structures

, 2003
In this paper we report the results of simulations of a 2D gravity driven, dissipative granular flow through a hopper system. Measurements of impulse distributions P(I) on the simulated system show flow-velocity-invariant behavior of the distribution for
A Ferguson, B Chakraborty, B Fisher, Corwin Eric, Landry James, Liu C. H.   +5 more
core   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Controllability of Impulsive Non–Linear Delay Dynamic Systems on Time Scale

IEEE Access, 2020
In this paper, we obtain the results of controllability for first order impulsive non–linear time varying delay dynamic systems and Hammerstein impulsive system on time scale, using the theory of fixed points such as Banach fixed point theorem ...
Akbar Zada, Luqman Alam, Poom Kumam, Wiyada Kumam, Gohar Ali, Jehad Alzabut   +5 more
doaj   +1 more source

Integral Input-to-State Stability of Nonlinear Time-Delay Systems with Delay-Dependent Impulse Effects

, 2020
This paper studies integral input-to-state stability (iISS) of nonlinear impulsive systems with time-delay in both the continuous dynamics and the impulses. Several iISS results are established by using the method of Lyapunov-Krasovskii functionals.
Zhang, Kexue
core  

Picosecond timing of Microwave Cherenkov Impulses from High-Energy Particle Showers Using Dielectric-loaded Waveguides

, 2018
We report on the first measurements of coherent microwave impulses from high-energy particle-induced electromagnetic showers generated via the Askaryan effect in a dielectric-loaded waveguide.
Bynes, J., Fox, B., Gorham, P. W., Hast, C., Hill, B., Jobe, K., Miki, C., Prechelt, R., Rotter, B., Saltzberg, D. P., Varner, G. S., Wissel, S. A., Zekioglu, S.   +12 more
core   +1 more source

Stationary and impulsive injection of electron beams in converging magnetic field [PDF]

, 2009
In this work we study time-dependent precipitation of an electron beam injected into a flaring atmosphere with a converging magnetic field by considering collisional and Ohmic losses with anisotropic scattering and pitch angle diffusion.
Siversky, Taras V., Zharkova, Valentina V.   +1 more
core   +1 more source