Results 151 to 160 of about 216,838 (308)
Imputing Parental Genotypes Through Mendelian Imputation
Behavior geneticsMendelian imputation is a promising method for imputing missing parental genotypes and estimating direct and indirect genetic effects. While the method has clear scientific benefits, so far there has been little reflection on its legal and ethical implications.
van de Weijer, Margot P. +4 more
openaire +1 more source
Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
Advanced Science, EarlyView.ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
Measuring Inequality Using Censored Data: A Multiple Imputation Approach [PDF]
To measure income inequality with right censored (topcoded) data, we propose multiple imputation for censored observations using draws from Generalized Beta of the Second Kind distributions to provide partially synthetic datasets analyzed using complete ...
Shuaizhang Feng +3 more
core +2 more sources
Multiple imputation of time series: an application to the construction of historical price indexes [PDF]
Time series in many areas of application, and notably in the social sciences, are frequently incomplete. This is particularly annoying when we need to have complete data, for instance to compute indexes as a weighted average of values from a number of ...
Tusell Palmer, Fernando Jorge
core
Advanced Science, EarlyView.This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen +15 more
wiley +1 more source
MANOVA modelling of a chiropractic longitudinal study using multiple imputation
, 2012 The purpose of this report is to present the detailed statistical analysis of a randomised, placebo-controlled trial comparing two different treatment modalities to an intervention of no known benefit for people with acute or subacute thoracic spine pain.
Clarke, B.R., Bowden, R.S., Walker, B.F.
core
MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes
Advanced Science, EarlyView.A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak +19 more
wiley +1 more source
A comparison of two methods of estimating propensity scores after multiple imputation
, 2011 In many observational studies, analysts estimate treatment effects using propensity scores, e.g., by matching or sub classifying on the scores. When some values of the covariates are missing, analysts can use multiple imputation to fill in the missing ...
Reiter, Jerome P., Mitra, Robin
core
Advanced Science, EarlyView.This study applied AI to quantify multidimensional body composition from CT images in gastric cancer and healthy controls. Distinct sex‐specific patterns and disease‐related alterations were identified and were associated with survival. Higher muscle and fat measures were linked to improved outcomes.
Tianxiang Li +13 more
wiley +1 more source
A new approach for disclosure control in the IAB Establishment Panel : multiple imputation for a better data access [PDF]
"For micro-datasets considered for release as scientific or public use files, statistical agencies have to face the dilemma of guaranteeing the confidentiality of survey respondents on the one hand and offering sufficiently detailed data on the other ...
Rässler, Susanne +4 more
core