Results 171 to 180 of about 248,303 (301)

Did you miss me? Making the most of digital phenotyping data by imputing missingness with point process models: observational study. [PDF]

BMJ Health Care Inform
Leaning IE, Costanzo A, Jagesar R, Knol L, Tjeerdsma S, Tyborowska A, Ikani N, Reus LM, Visser PJ, Kas MJ, Beckmann CF, Ruhé HG, Marquand AF.   +12 more
europepmc   +1 more source

A comparison of two methods of estimating propensity scores after multiple imputation

, 2011
In many observational studies, analysts estimate treatment effects using propensity scores, e.g., by matching or sub classifying on the scores. When some values of the covariates are missing, analysts can use multiple imputation to fill in the missing ...
Reiter, Jerome P., Mitra, Robin
core  

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

A simple demonstration of a privacy-preserving de-centralised genotype imputation workflow. [PDF]

PLoS One
Letaillandier A, Picard-Druet D, Ludwig TE, Marenne G, Herzig AF.   +4 more
europepmc   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

A Practical Workflow for Correcting Kit-Specific Effects in Whole-Exome Sequencing Data. [PDF]

Methods Protoc
Jarosz L, Ochocki M, Merta J, Pusztai L, Marczyk M.   +4 more
europepmc   +1 more source

A new approach for disclosure control in the IAB Establishment Panel : multiple imputation for a better data access [PDF]

"For micro-datasets considered for release as scientific or public use files, statistical agencies have to face the dilemma of guaranteeing the confidentiality of survey respondents on the one hand and offering sufficiently detailed data on the other ...
Rässler, Susanne, Bender, Stefan, Drechsler, Jörg, Dundler, Agnes, Zwick, Thomas   +4 more
core  

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

A population-specific genomic reference panel for Taiwan: NHRI-RP-1. [PDF]

J Biomed Sci
Cheng KH, Chen YR, Chung RH, Lin MW, Weng HY, Lin YR, Lin YF, Hsu JS, Kirby R, Chuang SY, Liu YL, Huang SK, Chen WJ, Hsu CC, Sheu WH, Tsai SF.   +15 more
europepmc   +1 more source

Missing data imputation: focusing on single imputation.

Annals of translational medicine, 2016
Complete case analysis is widely used for handling missing data, and it is the default method in many statistical packages. However, this method may introduce bias and some useful information will be omitted from analysis. Therefore, many imputation methods are developed to make gap end. The present article focuses on single imputation.
openaire   +1 more source