Results 31 to 40 of about 375,599 (291)

Optimizing Selection of the Reference Population for Genotype Imputation From Array to Sequence Variants

open access: yesFrontiers in Genetics, 2019
Imputation of high-density genotypes to whole-genome sequences (WGS) is a cost-effective method to increase the density of available markers within a population.
Adrien M. Butty   +9 more
doaj   +1 more source

Improving Cardiovascular Disease Prediction by Integrating Imputation, Imbalance Resampling, and Feature Selection Techniques into Machine Learning Model

open access: yesIJCCS (Indonesian Journal of Computing and Cybernetics Systems), 2023
Cardiovascular disease (CVD) is the leading cause of death worldwide. Primary prevention is by early prediction of the disease onset. Using laboratory data from the National Health and Nutrition Examination Survey (NHANES) in 2017-2020 timeframe (N= 7 ...
Fadlan Hamid Alfebi, Mila Desi Anasanti
doaj   +1 more source

To Impute or Not To Impute in Untargeted Metabolomics─That is the Compositional Question [PDF]

open access: yesJournal of the American Society for Mass Spectrometry
ABSTRACT Untargeted metabolomics often produce large datasets with missing values, arising from biological or technical factors, which can undermine statistical analyses and lead to biased biological interpretations. Imputation methods, such as k-Nearest Neighbors (kNN) and Random Forest (RF) regression are commonly used but their ...
Dennis Dimitri Krutkin   +6 more
openaire   +2 more sources

A ‘Chief Error’ of Protestant Soteriology: Sin in the Justified and Early Modern Catholic Theology

open access: yesPerichoresis: The Theological Journal of Emanuel University, 2020
Catholic theologians after Trent saw the Protestant teaching about the remnants of original sin in the justified as one of the ‘chief ’ errors of Protestant soteriology.
Gaetano Matthew T.
doaj   +1 more source

Enhancing water use efficiency in precision irrigation: data-driven approaches for addressing data gaps in time series

open access: yesFrontiers in Water, 2023
Real-time soil matric potential measurements for determining potato production's water availability are currently used in precision irrigation. It is well known that managing irrigation based on soil matric potential (SMP) helps increase water use ...
Mohammad Zeynoddin   +2 more
doaj   +1 more source

Comparing Methods to Select Candidates for Re-Genotyping to Impute Higher-Density Genotype Data in a Japanese Black Cattle Population: A Case Study

open access: yesAnimals, 2023
As optimization methods to identify the best animals for dense genotyping to construct a reference population for genotype imputation, the MCA and MCG methods, which use the pedigree-based additive genetic relationship matrix (A matrix) and the genomic ...
Shinichiro Ogawa   +3 more
doaj   +1 more source

Inclusion of imputed genotypes from non-genotyped dairy cattle in a Thai multibreed genomic-polygenic evaluation [PDF]

open access: yesAnimal Bioscience
Objective This study assessed the impact of incorporating imputed single nucleotide polymorphism (SNP) information from non-genotyped animals on genomic-polygenic evaluations in a Thai multibreed dairy population under various levels of imputation ...
Danai Jattawa   +3 more
doaj   +1 more source

Whole Exome Sequencing Enhanced Imputation Identifies 85 Metabolite Associations in the Alpine CHRIS Cohort

open access: yesMetabolites, 2022
Metabolites are intermediates or end products of biochemical processes involved in both health and disease. Here, we take advantage of the well-characterized Cooperative Health Research in South Tyrol (CHRIS) study to perform an exome-wide association ...
Eva König   +11 more
doaj   +1 more source

Genotype Imputation to Improve the Cost-Efficiency of Genomic Selection in Rabbits

open access: yesAnimals, 2021
Genomic selection uses genetic marker information to predict genomic breeding values (gEBVs), and can be a suitable tool for selecting low-hereditability traits such as litter size in rabbits.
Enrico Mancin   +3 more
doaj   +1 more source

Imputation Estimators Partially Correct for Model Misspecification [PDF]

open access: yes, 2010
Inference problems with incomplete observations often aim at estimating population properties of unobserved quantities. One simple way to accomplish this estimation is to impute the unobserved quantities of interest at the individual level and then take ...
Minin, Vladimir N.   +2 more
core   +1 more source

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