Results 31 to 40 of about 230,992 (300)

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

open access: yesPLoS Genetics, 2009
Genotype imputation methods are now being widely used in the analysis of genome-wide association studies. Most imputation analyses to date have used the HapMap as a reference dataset, but new reference panels (such as controls genotyped on multiple SNP ...
Bryan N. Howie, P. Donnelly, J. Marchini
semanticscholar   +1 more source

Inclusion of imputed genotypes from non-genotyped dairy cattle in a Thai multibreed genomic-polygenic evaluation [PDF]

open access: yesAnimal Bioscience
Objective This study assessed the impact of incorporating imputed single nucleotide polymorphism (SNP) information from non-genotyped animals on genomic-polygenic evaluations in a Thai multibreed dairy population under various levels of imputation ...
Danai Jattawa   +3 more
doaj   +1 more source

Whole Exome Sequencing Enhanced Imputation Identifies 85 Metabolite Associations in the Alpine CHRIS Cohort

open access: yesMetabolites, 2022
Metabolites are intermediates or end products of biochemical processes involved in both health and disease. Here, we take advantage of the well-characterized Cooperative Health Research in South Tyrol (CHRIS) study to perform an exome-wide association ...
Eva König   +11 more
doaj   +1 more source

Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls

open access: yesBritish medical journal, 2009
Most studies have some missing data. Jonathan Sterne and colleagues describe the appropriate use and reporting of the multiple imputation approach to dealing with ...
J. Sterne   +7 more
semanticscholar   +1 more source

Genotype Imputation to Improve the Cost-Efficiency of Genomic Selection in Rabbits

open access: yesAnimals, 2021
Genomic selection uses genetic marker information to predict genomic breeding values (gEBVs), and can be a suitable tool for selecting low-hereditability traits such as litter size in rabbits.
Enrico Mancin   +3 more
doaj   +1 more source

Design of an imputation methodology by random selection using regression trees

open access: yesBulletin of Computational Applied Mathematics, 2021
One of the biggest issues in the information collection stage is the absence of data, this research focuses specifically on the scenario when the loss is partial, completely random and the data is quantitative. There are classic techniques to impute data,
Lelly Useche   +3 more
doaj  

Completing a molecular timetree of apes and monkeys

open access: yesFrontiers in Bioinformatics, 2023
The primate infraorder Simiiformes, comprising Old and New World monkeys and apes, includes the most well-studied species on earth. Their most comprehensive molecular timetree, assembled from thousands of published studies, is found in the TimeTree ...
Jack M. Craig   +12 more
doaj   +1 more source

Comparison of different imputation methods from low- to high-density panels using Chinese Holstein cattle

open access: yesAnimal, 2013
Imputation of high-density genotypes from low- or medium-density platforms is a promising way to enhance the efficiency of whole-genome selection programs at low cost.
Z. Weng   +5 more
doaj   +1 more source

Genomic inbreeding coefficients using imputed genotypes: Assessing different estimators in Holstein-Friesian dairy cows

open access: yesJournal of Dairy Science, 2022
: The objective of this study was to estimate inbreeding coefficients in Holstein dairy cattle using imputed SNPs data. A data set of 95,540 Italian Holstein dairy cows from the routine genomic evaluations of the Italian National Association of Holstein,
Christos Dadousis   +7 more
doaj   +1 more source

Multiple Imputation by Chained Equations: What is it and how does it work?

open access: yesInternational Journal of Methods in Psychiatric Research, 2011
Multivariate imputation by chained equations (MICE) has emerged as a principled method of dealing with missing data. Despite properties that make MICE particularly useful for large imputation procedures and advances in software development that now make ...
M. Azur   +3 more
semanticscholar   +1 more source

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