Results 31 to 40 of about 216,838 (308)

A Method of Pruning and Random Replacing of Known Values for Comparing Missing Data Imputation Models for Incomplete Air Quality Time Series

Applied Sciences, 2022
The data obtained from air quality monitoring stations, which are used to carry out studies using data mining techniques, present the problem of missing values. This paper describes a research work on missing data imputation.
Luis Alfonso Menéndez García, Marta Menéndez Fernández, Violetta Sokoła-Szewioła, Laura Álvarez de Prado, Almudena Ortiz Marqués, David Fernández López, Antonio Bernardo Sánchez   +6 more
doaj   +1 more source

Sequencing genes in silico using single nucleotide polymorphisms

BMC Genetics, 2012
Background The advent of high throughput sequencing technology has enabled the 1000 Genomes Project Pilot 3 to generate complete sequence data for more than 906 genes and 8,140 exons representing 697 subjects.
Zhang Xinyi, Zhang Bo, Li Shuying, Huang Xin, Hansen John A, Zhao Lue   +5 more
doaj   +1 more source

PhosR enables processing and functional analysis of phosphoproteomic data

Cell Reports, 2021
Summary: Mass spectrometry (MS)-based phosphoproteomics has revolutionized our ability to profile phosphorylation-based signaling in cells and tissues on a global scale.
Hani Jieun Kim, Taiyun Kim, Nolan J. Hoffman, Di Xiao, David E. James, Sean J. Humphrey, Pengyi Yang   +6 more
doaj   +1 more source

Performance of genotype imputation for rare variants identified in exons and flanking regions of genes. [PDF]

, 2011
Genotype imputation has the potential to assess human genetic variation at a lower cost than assaying the variants using laboratory techniques. The performance of imputation for rare variants has not been comprehensively studied.
Margaret Gelder Ehm, Sharon R. Browning, Slater, Andrew J., Browning, Brian L., Aponte, Jennifer L., Browning Sharon R., Ehm, Margaret Gelder, Stephanie L Chissoe, Whittaker John C., Mooser, Vincent E., Sharon R Browning, Li, Li, Vincent E. Mooser, Jennifer L. Aponte, Brian L Browning, Li Yun, Whittaker, John C., Jennifer L Aponte, Browning, Brian L, Ehm Margaret Gelder, Browning, Sharon R, Whittaker, John C, Nelson, Matthew R, Mooser Vincent E., Aponte, Jennifer L, John C. Whittaker, Matthew R Nelson, Andrew J Slater, Vincent E Mooser, Browning Brian L., Mooser, Vincent E, Nelson Matthew R., Nelson, Matthew R., Li, Yun, John C Whittaker, Yun Li, Chissoe Stephanie L., Browning, Sharon R., Kong Xiangyang, Slater, Andrew J, Chissoe, Stephanie L, Matthew R. Nelson, Chissoe, Stephanie L., Li Li, Andrew J. Slater, Stephanie L. Chissoe, Xiangyang Kong, Slater Andrew J., Kong, Xiangyang, Aponte Jennifer L., Brian L. Browning   +50 more
core   +1 more source

The Challenges of Chromosome Y Analysis and the Implications for Chronic Kidney Disease

Frontiers in Genetics, 2019
The role of chromosome Y in chronic kidney disease (CKD) remains unknown, as chromosome Y is typically excluded from genetic analysis in CKD. The complex, sex-specific presentation of CKD could be influenced by chromosome Y genetic variation, but there ...
Kerry Anderson, Marisa Cañadas-Garre, Robyn Chambers, Alexander Peter Maxwell, Alexander Peter Maxwell, Amy Jayne McKnight   +5 more
doaj   +1 more source

Decoding the diversity of killer immunoglobulin-like receptors by deep sequencing and a high-resolution imputation method

Cell Genomics, 2022
Summary: The killer cell immunoglobulin-like receptor (KIR) recognizes human leukocyte antigen (HLA) class I molecules and modulates the function of natural killer cells.
Saori Sakaue, Kazuyoshi Hosomichi, Jun Hirata, Hirofumi Nakaoka, Keiko Yamazaki, Makoto Yawata, Nobuyo Yawata, Tatsuhiko Naito, Junji Umeno, Takaaki Kawaguchi, Toshiyuki Matsui, Satoshi Motoya, Yasuo Suzuki, Hidetoshi Inoko, Atsushi Tajima, Takayuki Morisaki, Koichi Matsuda, Yoichiro Kamatani, Kazuhiko Yamamoto, Ituro Inoue, Yukinori Okada   +20 more
doaj   +1 more source

Cost-effectiveness in clinical trials : using multiple imputation to deal with incomplete cost data [PDF]

, 2007
Background: Cost-effectiveness has become an important outcome in many clinical trials and has resulted in the collection of resource use data and the calculation of costs for individual patients.
Burton, Andrea, Billingham, Lucina Jane, Bryan, Stirling, Billingham, Lucinda; id_orcid, Burton, A   +4 more
core   +1 more source

Learning-Based Adaptive Imputation Methodwith kNN Algorithm for Missing Power Data

Energies, 2017
This paper proposes a learning-based adaptive imputation method (LAI) for imputing missing power data in an energy system. This method estimates the missing power data by using the pattern that appears in the collected data. Here, in order to capture the
Minkyung Kim, Sangdon Park, Joohyung Lee, Yongjae Joo, Jun Kyun Choi   +4 more
doaj   +1 more source

Data‐Driven Estimation of Groundwater Level Time‐Series at Unmonitored Sites Using Comparative Regional Analysis

Water Resources Research, 2023
A new method is presented to efficiently estimate daily groundwater level time series at unmonitored sites by linking groundwater dynamics to local hydrogeological system controls.
E. Haaf, M. Giese, T. Reimann, R. Barthel   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source